Kinase profiling results of kinases in KIF 2C6IA_DT1 (CDK2, PDB code: 2C6I, chain A)
Template Kinase: CDK2
Template inhibitor: 2c6i

 27 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ROCK2AGC
CDK2CMGC
CDK4CMGC
CLK2CMGC
CLK4CMGC
AURKAOther
AURKBOther
AURKCOther
EIF2AK2Other
TTKOther
PAK7STE
ABL1TK
TNK2TK
FERTK
FGFR2TK
JAK2TK
JAK3TK
METTK
SRCTK
YES1TK
LCKTK
PTK6TK
BMXTK
NTRK3TK
LIMK1TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
ROCK2AGC 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK4CMGC 
CDK6CMGC 
CDK6CMGC 
CLK2CMGC 
CLK4CMGC 
AURKAOther 
AURKBOther 
AURKCOther 
TTKOther 
PAK7STE 
ABL1TK 
BMXTK 
FERTK 
FGFR2TK 
JAK2TK 
JAK3TK 
LCKTK 
METTK 
NTRK3TK 
PTK6TK 
SRCTK 
TNK2TK 
YES1TK 
LIMK1TKL