Kinase profiling results of kinases in KIF 2R3FA_SC8 (CDK2, PDB code: 2R3F, chain A)
Template Kinase: CDK2
Template inhibitor: 2c68

22 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
AKT2AGC 
ROCK2AGC 
PRKCDAGC 
PRKCQAGC 
CDK2CMGC 
CDK4CMGC 
CDC2L6CMGC 
CDK8CMGC 
GSK3BCMGC 
MAPK14CMGC 
AURKBOther 
CHUKOther 
PLK1Other 
DDR1TK 
PTK2TK 
JAK2TK 
JAK3TK 
SRCTK 
LCKTK 
PTK6TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
AKT1AGC     
AKT2AGC     
PRKCDAGC     
PRKCQAGC     
ROCK2AGC     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK4CMGC     
GSK3BCMGC     
MAPK14CMGC     
AURKBOther     
CHUKOther     
PLK1Other     
JAK2TK     
JAK3TK     
LCKTK     
PTK2TK     
PTK6TK     
SRCTK