Kinase profiling results of kinases in KIF 2VTNA_LZ7 (CDK2, PDB code: 2VTN, chain A)
Template Kinase: CDK2
Template inhibitor: pyrazole amide, 18

8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK14CMGC 
AURKAOther 
NEK2Other 
MAP2K1STE 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
GSK3ACMGC     
GSK3BCMGC     
MAPK14CMGC     
AURKAOther     
NEK2Other     
MAP2K1STE