Kinase profiling results of kinases in KIF 2W05A_FRT (CDK2, PDB code: 2W05, chain A)
Template Kinase: CDK2
Template inhibitor: 2w05

 7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK4CMGC
CDK9CMGC
AURKAOther
AURKBOther
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CDC2CMGC
CDC2CMGC
CDK2CMGC
CDK4CMGC
CDK9CMGC
AURKAOther
AURKBOther
SRCTK