Kinase profiling results of kinases in KIF 2W17A_I19 (CDK2, PDB code: 2W17, chain A)
Template Kinase: CDK2
Template inhibitor: DB07936

25 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C
PDPK1AGC     
CDK2CMGC     
CDK4CMGC     
CDK5CMGC     
CDKL1CMGC     
GSK3BCMGC     
MAPK10CMGC     
MAPK8CMGC     
MAPK9CMGC     
AURKAOther     
AURKBOther     
PLK1Other     
PLK2Other     
PLK3Other     
ABL1TK     
FGFR1TK     
JAK2TK     
JAK3TK     
METTK     
SRCTK     
HCKTK     
LCKTK     
LYNTK     
PTK6TK     

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C C C
PDPK1AGC         
CDC2CMGC         
CDC2CMGC         
CDK2CMGC         
CDK4CMGC         
CDK5CMGC         
GSK3BCMGC         
MAPK10CMGC         
MAPK8CMGC         
MAPK9CMGC         
AURKAOther         
AURKBOther         
PLK1Other         
PLK2Other         
PLK3Other         
ABL1TK         
FGFR1TK         
HCKTK         
JAK2TK         
JAK3TK         
LCKTK         
LYNTK         
METTK         
PTK6TK         
SRCTK