Kinase profiling results of kinases in KIF 3LFNA_A27 (CDK2, PDB code: 3LFN, chain A)
Template Kinase: CDK2
Template inhibitor: DNC010577

14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
MARK1CAMK
PIM2CAMK
CDK2CMGC
CDK4CMGC
GSK3ACMGC
GSK3BCMGC
MAPK10CMGC
AURKAOther
PLK1Other
ABL1TK
METTK
SRCTK
ITKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
MARK1CAMK
PIM2CAMK
CDC2CMGC
CDC2CMGC
CDK2CMGC
CDK4CMGC
GSK3ACMGC
GSK3BCMGC
MAPK10CMGC
AURKAOther
PLK1Other
ABL1TK
ITKTK
METTK
SRCTK