Kinase profiling results of kinases in KIF 2UV2A_GVD (SLK, PDB code: 2UV2, chain A)
Template Kinase: SLK
Template inhibitor: pyrido[4,3-d]pyrimidine deriv. 4n

 21 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PRKCDAGC
PRKCQAGC
PRKCEAGC
CAMK2BCAMK
CAMK2DCAMK
CHEK1CAMK
STK17BCAMK
CDK2CMGC
MAPK14CMGC
AURKAOther
AURKBOther
SLKSTE
ABL1TK
EGFRTK
PTK2TK
FGFR1TK
JAK2TK
JAK3TK
RETTK
BRAFTKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PRKCDAGC
PRKCEAGC
PRKCQAGC
CAMK2BCAMK
CAMK2DCAMK
CHEK1CAMK
CDC2CMGC
CDC2CMGC
CDK2CMGC
MAPK14CMGC
AURKAOther
AURKBOther
SLKSTE
ABL1TK
EGFRTK
FGFR1TK
JAK2TK
JAK3TK
PTK2TK
RETTK
BRAFTKL