Kinase profiling results of kinases in KIF 3EFKA_MT4 (MET, PDB code: 3EFK, chain A)
Template Kinase: MET
Template inhibitor: pyrimidone, 50

 9 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
MYO3ASTE 
DDR2TK 
PTK2BTK 
IGF1RTK 
INSRRTK 
METTK 
NTRK1TK 
FLT4TK 
KDRTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
DDR2TK
FLT4TK
IGF1RTK
INSRRTK
KDRTK
METTK
NTRK1TK
PTK2BTK