Kinase profiling results of kinases in KIF 3L9MA_L9M (PRKACA, PDB code: 3L9M, chain A)
Template Kinase: PRKACA
Template inhibitor: VX_680

 37 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
AKT2AGC 
AKT3AGC 
CITAGC 
ROCK1AGC 
ROCK2AGC 
GRK4AGC 
GRK7AGC 
PRKACAAGC 
PRKACBAGC 
PRKXAGC 
PRKG1AGC 
PRKG2AGC 
CAMK2ACAMK 
CAMK2BCAMK 
NUAK2CAMK 
DAPK1CAMK 
PRKD3CAMK 
CHEK2CAMK 
CDK2CMGC 
CDK3CMGC 
CDC2L5CMGC 
CDKL2CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK14CMGC 
ICKCMGC 
AURKAOther 
AURKBOther 
AURKCOther 
EIF2AK2Other 
PLK4Other 
ULK1Other 
ULK2Other 
PAK7STE 
MAP3K7TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
AKT1AGC 
AKT2AGC 
AKT3AGC 
GRK4AGC 
GRK7AGC 
PRKACAAGC 
PRKG1AGC 
PRKG2AGC 
PRKXAGC 
ROCK1AGC 
ROCK2AGC 
CAMK2ACAMK 
CAMK2BCAMK 
CHEK2CAMK 
DAPK1CAMK 
NUAK2CAMK 
PRKD3CAMK 
CDK2CMGC 
CDK3CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK14CMGC 
AURKAOther 
AURKBOther 
AURKCOther 
ULK1Other 
ULK2Other 
PAK7STE 
MAP3K7TKL