Kinase profiling results of kinases in KIF 2C3LA_IDZ (CHEK1, PDB code: 2C3L, chain A)
Template Kinase: CHEK1
Template inhibitor: IDZ

 14 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ROCK2AGC
PDPK1AGC
PRKG2AGC
CHEK1CAMK
MKNK2CAMK
PIM1CAMK
CHEK2CAMK
CDK5CMGC
GSK3BCMGC
MAPK10CMGC
MAPK14CMGC
AURKAOther
AURKBOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PDPK1AGC    
PRKG2AGC    
ROCK2AGC    
CHEK1CAMK    
CHEK2CAMK    
MKNK2CAMK    
PIM1CAMK    
CDC2CMGC    
CDC2CMGC    
CDK5CMGC    
GSK3BCMGC    
MAPK10CMGC    
MAPK14CMGC    
AURKAOther    
AURKBOther