Protein-Protein Interaction Search

Input an interacting protein pair as a query to search its homologous interactions across multiple species

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Query protein pair (sequences in FASTA format or UniProt ID) :
Input sequences in FASTA format
	Interacting partner 1:	>sp|P61967|AP1S1_MOUSE MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG GDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA
	Interacting partner 2:	>sp|P22892|AP1G1_MOUSE MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLG YPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQG LALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATK NLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGI SDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIK SESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVS IKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHID TIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCI GEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPSEIVQ TNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLL GDITLTGAPAAAPTPASVPQISQPPFLLDGLSSQPLFNDIAPGIPSITAYSKNGLKIEFT FERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSVVPAFNTGTITQ VIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ
Input UniProt accession numbers (Ex: AP1S1_MOUSE)
	Interacting partner 1:              Interacting partner 2:
			Quick link of search result
Options:
	E-value cut-off threshold for homolog searching
	10 10-1 10-10 (Default) Other:  (Ex: -50 = 10-50)
	Joint E-value
	10-100 10-40 (Default) 10-10 Other:  (Ex: -50 = 10-50)
	Number of homologous interactions in each species ( Ranking by Joint E-value )
	Best-match Three All (Default) Other:
	The conservation ratio (CRD) of a domain-domain pair
	1.00 All 0.60 (Default) Other:  (Input Range: 0.01 ~ 0.99)
	The conservation ratio (CRF) of a molecular function term pair
	1.00 All 0.60 (Default) Other:  (Input Range: 0.01 ~ 0.99)
	Choose output species
	Homo sapiens Caenorhabditis elegans Others (Taxonomy ID) Ex: 9913;9598;...        Drosophila melanogaster Arabidopsis thaliana Saccharomyces cerevisiae Mus musculus Rattus norvegicus All (Default)
Last updated 2009/04/11