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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
10 RAF1 related diseases
hsa05034
Alcoholism
hsa05152
Tuberculosis
hsa05160
Hepatitis C
hsa05164
Influenza A
hsa05215
Prostate cancer
hsa05218
Melanoma
hsa05220
Chronic myeloid leukemia
hsa05221
Acute myeloid leukemia
611554
LEOPARD syndrome 2
611553
Noonan syndrome 5
Summary of query kinase
Query kinase
RAF1 (
P04049
)
Kinase group
TKL
Number of conformation types
1
Number of structural templates
1 (
Total 345 inhibitors
)
Number of RAF1 related diseases
10 (
hsa05034
hsa05152
hsa05160
hsa05164
hsa05215
hsa05218
hsa05220
hsa05221
...
)
Number of allelic variants
4 (
L613V
P261S
S257L
T491R
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
1
3OMVA_SM5
(RAF1)
TKL
pyrazole bas...
I
2
27
16
A
3OMVA_SM5
(RAF1)
TKL
pyrazole bas...
I
2
27
16
2
27
16