Summary of query kinase
Query kinase AKT2 (P31751)
Kinase group AGC
Number of inhibitors 337
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 AKT2 A-443654 BD00015131 n/a 0.5 n/a n/a n/a BindingDB BindingDB
1 AKT2 CHEMBL1098938 BD50316183 2 10 n/a n/a n/a BindingDB BindingDB
2 AKT2 CHEMBL470597 BD50278770 3 10 n/a n/a n/a BindingDB BindingDB
3 AKT2 CHEMBL482536 BD50278099 4 10 n/a n/a n/a BindingDB BindingDB
4 AKT2 6-phenylpurine compound 18 BD00016231 n/a 10 n/a n/a n/a BindingDB BindingDB
5 AKT2 CHEMBL447328 BD50256718 n/a 10 n/a n/a n/a BindingDB BindingDB
6 AKT2 CHEMBL502854 BD50256716 n/a 10.4 n/a n/a n/a BindingDB BindingDB
7 AKT2 CHEMBL508861 BD50256720 n/a 10.5 n/a n/a n/a BindingDB BindingDB
8 AKT2 oxadiazole-containing compound, 1 BD00024989 n/a 1000 n/a n/a n/a BindingDB BindingDB
9 AKT2 oxadiazole-containing compound, 6 BD00024993 n/a 10000 n/a n/a n/a BindingDB BindingDB
10 AKT2 2,3,5-trisubstituted pyridine, 13e BD00024897 n/a 101 n/a n/a n/a BindingDB BindingDB
11 AKT2 CHEMBL448826 BD50243766 n/a 102 n/a n/a n/a BindingDB BindingDB
12 AKT2 2,3,5-trisubstituted pyridine, 3 BD00024884 n/a 105 n/a n/a n/a BindingDB BindingDB
13 AKT2 CHEMBL1258779 BD50327805 n/a 1067 n/a n/a n/a BindingDB BindingDB
14 AKT2 Pyridopyrimidine, 14a BD00024877 n/a 107.2 n/a n/a n/a BindingDB BindingDB
15 AKT2 CHEMBL599847 BD50307964 n/a 11 n/a n/a n/a BindingDB BindingDB
16 AKT2 CHEMBL598207 BD50307965 n/a 11 n/a n/a n/a BindingDB BindingDB
17 AKT2 isoquinoline-5-sulfonamide 5 BD00015193 n/a 1100 n/a n/a n/a BindingDB BindingDB
18 AKT2 CHEMBL506827 BD50243289 n/a 116 n/a n/a n/a BindingDB BindingDB
19 AKT2 Pyridopyrimidine, 12f BD00024861 n/a 1160 n/a n/a n/a BindingDB BindingDB
20 AKT2 isoquinoline-5-sulfonamide 3 BD00015191 n/a 1170 n/a n/a n/a BindingDB BindingDB
21 AKT2 pyrazinone 14b BD00015153 n/a 1179 n/a n/a n/a BindingDB BindingDB
22 AKT2 CHEMBL1258330 BD50327797 n/a 118 n/a n/a n/a BindingDB BindingDB
23 AKT2 CHEMBL593490 BD50305878 n/a 12 n/a n/a n/a BindingDB BindingDB
24 AKT2 CHEMBL593813 BD50306163 n/a 12 n/a n/a n/a BindingDB BindingDB
25 AKT2 CHEMBL599448 BD50307966 n/a 12 n/a n/a n/a BindingDB BindingDB
26 AKT2 CHEMBL598013 BD50307967 n/a 12 n/a n/a n/a BindingDB BindingDB
27 AKT2 CHEMBL1079175 BD50313650 n/a 12 n/a n/a n/a BindingDB BindingDB
28 AKT2 quinoline 5 BD00015170 n/a 1205 n/a n/a n/a BindingDB BindingDB
29 AKT2 2,3,5-trisubstituted pyridine, 13d BD00024896 n/a 121 n/a n/a n/a BindingDB BindingDB
30 AKT2 Pyridopyrimidine, 12c BD00024858 n/a 1242 n/a n/a n/a BindingDB BindingDB
31 AKT2 CHEMBL512135 BD50278603 125 125 n/a n/a n/a BindingDB BindingDB
32 AKT2 CHEMBL1258442 BD50327799 n/a 1288 n/a n/a n/a BindingDB BindingDB
33 AKT2 Pyridopyrimidine, 12a BD00024856 n/a 1299 n/a n/a n/a BindingDB BindingDB
34 AKT2 GSK690693 BD00025013 4 13 n/a n/a n/a BindingDB BindingDB
35 AKT2 CHEMBL469590 BD50278693 8 13 n/a n/a n/a BindingDB BindingDB
36 AKT2 oxadiazole-containing compound, 3e BD00025011 n/a 13 n/a n/a n/a BindingDB BindingDB
37 AKT2 oxadiazole-containing compound, 3h BD00025014 n/a 13 n/a n/a n/a BindingDB BindingDB
38 AKT2 CHEMBL595459 BD50306158 n/a 13 n/a n/a n/a BindingDB BindingDB
39 AKT2 CHEMBL505848 BD50243274 n/a 130 n/a n/a n/a BindingDB BindingDB
40 AKT2 CHEMBL594755 BD50306161 n/a 130 n/a n/a n/a BindingDB BindingDB
41 AKT2 Pyridopyrimidine, 13g BD00024874 n/a 1304 n/a n/a n/a BindingDB BindingDB
42 AKT2 CHEMBL447044 BD50243781 n/a 138 n/a n/a n/a BindingDB BindingDB
43 AKT2 Pyridopyrimidine, 12e BD00024860 n/a 1381 n/a n/a n/a BindingDB BindingDB
44 AKT2 CHEMBL597183 BD50307968 n/a 14 n/a n/a n/a BindingDB BindingDB
45 AKT2 CHEMBL445464 BD50256719 n/a 14.6 n/a n/a n/a BindingDB BindingDB
46 AKT2 CHEMBL503270 BD50243277 n/a 140 n/a n/a n/a BindingDB BindingDB
47 AKT2 quinoxaline 16d BD00015165 n/a 144 n/a n/a n/a BindingDB BindingDB
48 AKT2 CHEMBL449200 BD50243282 n/a 146 n/a n/a n/a BindingDB BindingDB
49 AKT2 CHEMBL1258550 BD50327800 n/a 1485 n/a n/a n/a BindingDB BindingDB
50 AKT2 CHEMBL593374 BD50306155 n/a 15 n/a n/a n/a BindingDB BindingDB
51 AKT2 CHEMBL593375 BD50306156 n/a 15 n/a n/a n/a BindingDB BindingDB
52 AKT2 CHEMBL594072 BD50306165 n/a 15 n/a n/a n/a BindingDB BindingDB
53 AKT2 CHEMBL597819 BD50307969 n/a 15 n/a n/a n/a BindingDB BindingDB
54 AKT2 CHEMBL564972 BD50296931 n/a 1500 n/a n/a n/a BindingDB BindingDB
55 AKT2 tetrazolylypyridine 8e BD00015183 n/a 1501 n/a n/a n/a BindingDB BindingDB
56 AKT2 Pyridopyrimidine, 12g BD00024862 n/a 1514 n/a n/a n/a BindingDB BindingDB
57 AKT2 isoquinoline-5-sulfonamide 6 BD00015194 n/a 1530 n/a n/a n/a BindingDB BindingDB
58 AKT2 CHEMBL505758 BD50243773 n/a 154 n/a n/a n/a BindingDB BindingDB
59 AKT2 tetrazolylypyridine 8a BD00015179 n/a 157 n/a n/a n/a BindingDB BindingDB
60 AKT2 CHEMBL182101 BD50313649 n/a 157 n/a n/a n/a BindingDB BindingDB
61 AKT2 CHEMBL1099297 BD50316184 1 16 n/a n/a n/a BindingDB BindingDB
62 AKT2 CHEMBL446966 BD50243221 n/a 16 n/a n/a n/a BindingDB BindingDB
63 AKT2 CHEMBL453586 BD50243777 n/a 16 n/a n/a n/a BindingDB BindingDB
64 AKT2 CHEMBL604917 BD50307970 n/a 16 n/a n/a n/a BindingDB BindingDB
65 AKT2 CHEMBL1098316 BD50316194 n/a 16 n/a n/a n/a BindingDB BindingDB
66 AKT2 6-phenylpurine compound 7 BD00016225 n/a 1600 n/a n/a n/a BindingDB BindingDB
67 AKT2 isoquinoline-5-sulfonamide 48 BD00015216 n/a 1700 n/a n/a n/a BindingDB BindingDB
68 AKT2 isoquinoline-5-sulfonamide 55 BD00015219 n/a 1700 n/a n/a n/a BindingDB BindingDB
69 AKT2 Pyridopyrimidine, 12d BD00024859 n/a 1709 n/a n/a n/a BindingDB BindingDB
70 AKT2 tetrazolylypyridine 8c BD00015181 n/a 1720 n/a n/a n/a BindingDB BindingDB
71 AKT2 pyrazinone 14c BD00015155 n/a 1755 n/a n/a n/a BindingDB BindingDB
72 AKT2 Pyridopyrimidine, 12i BD00024864 n/a 1792 n/a n/a n/a BindingDB BindingDB
73 AKT2 pyrazole-based inhibitor 9 BD00016219 n/a 18 n/a n/a n/a BindingDB BindingDB
74 AKT2 CHEMBL603680 BD50307971 n/a 18 n/a n/a n/a BindingDB BindingDB
75 AKT2 CHEMBL503810 BD50243276 n/a 180 n/a n/a n/a BindingDB BindingDB
76 AKT2 CHEMBL507204 BD50243281 n/a 185 n/a n/a n/a BindingDB BindingDB
77 AKT2 quinoxaline 16e BD00015166 n/a 1877 n/a n/a n/a BindingDB BindingDB
78 AKT2 CHEMBL450266 BD50243278 n/a 188 n/a n/a n/a BindingDB BindingDB
79 AKT2 CHEMBL595944 BD50306157 n/a 19 n/a n/a n/a BindingDB BindingDB
80 AKT2 CHEMBL597818 BD50307972 n/a 19 n/a n/a n/a BindingDB BindingDB
81 AKT2 CHEMBL501612 BD50243288 n/a 190 n/a n/a n/a BindingDB BindingDB
82 AKT2 Pyridopyrimidine, 13b BD00024869 n/a 1909 n/a n/a n/a BindingDB BindingDB
83 AKT2 CHEMBL508098 BD50243287 n/a 192 n/a n/a n/a BindingDB BindingDB
84 AKT2 tetrazolylypyridine 8f BD00015184 n/a 1956 n/a n/a n/a BindingDB BindingDB
85 AKT2 CHEMBL598194 BD50307942 n/a 2.2 n/a n/a n/a BindingDB BindingDB
86 AKT2 CHEMBL508794 BD50256723 n/a 2.8 n/a n/a n/a BindingDB BindingDB
87 AKT2 6-phenylpurine compound 20 BD00016232 n/a 20 n/a n/a n/a BindingDB BindingDB
88 AKT2 oxadiazole-containing compound, 3c BD00025009 n/a 20 n/a n/a n/a BindingDB BindingDB
89 AKT2 CHEMBL597415 BD50307973 n/a 20 n/a n/a n/a BindingDB BindingDB
90 AKT2 CHEMBL1096634 BD50316190 n/a 20 n/a n/a n/a BindingDB BindingDB
91 AKT2 CHEMBL1096626 BD50316191 n/a 20 n/a n/a n/a BindingDB BindingDB
92 AKT2 CHEMBL1098939 BD50316201 n/a 20 n/a n/a n/a BindingDB BindingDB
93 AKT2 CHEMBL1096292 BD50316197 646 200 n/a n/a n/a BindingDB BindingDB
94 AKT2 pyrazole-based inhibitor 7 BD00016217 n/a 200 n/a n/a n/a BindingDB BindingDB
95 AKT2 CHEMBL1096290 BD50316188 n/a 200 n/a n/a n/a BindingDB BindingDB
96 AKT2 oxadiazole-containing compound, 7 BD00024994 n/a 204 n/a n/a n/a BindingDB BindingDB
97 AKT2 2,3-diphenylquinoxaline 5 BD00015149 n/a 2090 n/a n/a n/a BindingDB BindingDB
98 AKT2 Isoquinoline-pyridine, 10y BD00016978 n/a 21 n/a n/a n/a BindingDB BindingDB
99 AKT2 CHEMBL444136 BD50243220 n/a 21 n/a n/a n/a BindingDB BindingDB
100 AKT2 imidazoquinoxaline 16h BD00015169 n/a 210 n/a n/a n/a BindingDB BindingDB
101 AKT2 isoquinoline-5-sulfonamide 10 BD00015198 n/a 210 n/a n/a n/a BindingDB BindingDB
102 AKT2 CHEMBL606200 BD50307950 n/a 210 n/a n/a n/a BindingDB BindingDB
103 AKT2 Pyridopyrimidine, 13c BD00024870 n/a 2106 n/a n/a n/a BindingDB BindingDB
104 AKT2 2,3,5-trisubstituted pyridine, 10c BD00024887 n/a 22 n/a n/a n/a BindingDB BindingDB
105 AKT2 2,3,5-trisubstituted pyridine, 10f BD00024890 n/a 22 n/a n/a n/a BindingDB BindingDB
106 AKT2 CHEMBL454859 BD50243775 n/a 22 n/a n/a n/a BindingDB BindingDB
107 AKT2 isoquinoline-5-sulfonamide 12 BD00015200 n/a 2200 n/a n/a n/a BindingDB BindingDB
108 AKT2 CHEMBL499961 BD50243290 n/a 225 n/a n/a n/a BindingDB BindingDB
109 AKT2 CHEMBL213618 BD50188913 n/a 23 n/a n/a n/a BindingDB BindingDB
110 AKT2 CHEMBL502426 BD50243778 n/a 23 n/a n/a n/a BindingDB BindingDB
111 AKT2 CCT077373 BD00016222 n/a 230 n/a n/a n/a BindingDB BindingDB
112 AKT2 CHEMBL447558 BD50243291 n/a 230 n/a n/a n/a BindingDB BindingDB
113 AKT2 oxadiazole-containing compound, 4 BD00024991 n/a 2340 n/a n/a n/a BindingDB BindingDB
114 AKT2 Pyridopyrimidine, 1 BD00024881 n/a 239 n/a n/a n/a BindingDB BindingDB
115 AKT2 CHEMBL509747 BD50256717 n/a 24.1 n/a n/a n/a BindingDB BindingDB
116 AKT2 tetrazolylypyridine 8b BD00015180 n/a 248 n/a n/a n/a BindingDB BindingDB
117 AKT2 CHEMBL1099296 BD50316182 17 25 n/a n/a n/a BindingDB BindingDB
118 AKT2 CHEMBL520788 BD50278098 4 25 n/a n/a n/a BindingDB BindingDB
119 AKT2 CHEMBL1099276 BD50316192 5 25 n/a n/a n/a BindingDB BindingDB
120 AKT2 CHEMBL470598 BD50278771 6 25 n/a n/a n/a BindingDB BindingDB
121 AKT2 CHEMBL503980 BD50243769 n/a 25 n/a n/a n/a BindingDB BindingDB
122 AKT2 CHEMBL596583 BD50306154 n/a 25 n/a n/a n/a BindingDB BindingDB
123 AKT2 CHEMBL598448 BD50307974 n/a 25 n/a n/a n/a BindingDB BindingDB
124 AKT2 CHEMBL597803 BD50307975 n/a 25 n/a n/a n/a BindingDB BindingDB
125 AKT2 CHEMBL1095624 BD50316193 n/a 25 n/a n/a n/a BindingDB BindingDB
126 AKT2 CHEMBL1099290 BD50316195 n/a 25 n/a n/a n/a BindingDB BindingDB
127 AKT2 CHEMBL606467 BD50306159 n/a 250 n/a n/a n/a BindingDB BindingDB
128 AKT2 CHEMBL596990 BD50307951 n/a 250 n/a n/a n/a BindingDB BindingDB
129 AKT2 oxadiazole-containing compound, 5 BD00024992 n/a 2510 n/a n/a n/a BindingDB BindingDB
130 AKT2 CHEMBL451961 BD50243762 n/a 252 n/a n/a n/a BindingDB BindingDB
131 AKT2 pyridine-base inhibitor 1b BD00015022 n/a 257 n/a n/a n/a BindingDB BindingDB
132 AKT2 oxadiazole-containing compound, 8 BD00024995 n/a 2570 n/a n/a n/a BindingDB BindingDB
133 AKT2 Pyridopyrimidine, 13i BD00024876 n/a 26 n/a n/a n/a BindingDB BindingDB
134 AKT2 CHEMBL446134 BD50243215 n/a 26 n/a n/a n/a BindingDB BindingDB
135 AKT2 isoquinoline-5-sulfonamide 61 BD00015220 n/a 2600 n/a n/a n/a BindingDB BindingDB
136 AKT2 Pyridopyrimidine, 13e BD00024872 n/a 267 n/a n/a n/a BindingDB BindingDB
137 AKT2 CHEMBL504251 BD50243771 n/a 27 n/a n/a n/a BindingDB BindingDB
138 AKT2 CHEMBL597211 BD50307943 n/a 27 n/a n/a n/a BindingDB BindingDB
139 AKT2 tetrazolylypyridine 8g BD00015185 n/a 2746 n/a n/a n/a BindingDB BindingDB
140 AKT2 CHEMBL1258662 BD50327802 n/a 279 n/a n/a n/a BindingDB BindingDB
141 AKT2 2,3,5-trisubstituted pyridine, 10b BD00024886 n/a 28 n/a n/a n/a BindingDB BindingDB
142 AKT2 pyrazole-based inhibitor 8b BD00016221 n/a 280 n/a n/a n/a BindingDB BindingDB
143 AKT2 quinoxaline 16a BD00015162 n/a 281 n/a n/a n/a BindingDB BindingDB
144 AKT2 CHEMBL502113 BD50243279 n/a 284 n/a n/a n/a BindingDB BindingDB
145 AKT2 CHEMBL454210 BD50243772 n/a 29 n/a n/a n/a BindingDB BindingDB
146 AKT2 CHEMBL599848 BD50307976 n/a 29 n/a n/a n/a BindingDB BindingDB
147 AKT2 isoquinoline-5-sulfonamide 13 BD00015201 n/a 2900 n/a n/a n/a BindingDB BindingDB
148 AKT2 CHEMBL450772 BD50243767 n/a 297 n/a n/a n/a BindingDB BindingDB
149 AKT2 2,3,5-trisubstituted pyridine, 10h BD00024892 n/a 30 n/a n/a n/a BindingDB BindingDB
150 AKT2 pyrazoloquinoxaline 16g BD00015168 n/a 300 n/a n/a n/a BindingDB BindingDB
151 AKT2 H-89 BD00015211 n/a 300 n/a n/a n/a BindingDB BindingDB
152 AKT2 pyrazole-based inhibitor 4 BD00016214 n/a 3000 n/a n/a n/a BindingDB BindingDB
153 AKT2 Pyridopyrimidine, 13f BD00024873 n/a 301 n/a n/a n/a BindingDB BindingDB
154 AKT2 pyrazole-based inhibitor 8 BD00016218 n/a 31 n/a n/a n/a BindingDB BindingDB
155 AKT2 CHEMBL453995 BD50243782 n/a 31 n/a n/a n/a BindingDB BindingDB
156 AKT2 CHEMBL603197 BD50305882 n/a 31 n/a n/a n/a BindingDB BindingDB
157 AKT2 CHEMBL603262 BD50307977 n/a 31 n/a n/a n/a BindingDB BindingDB
158 AKT2 cyanopyridine 7a BD00015172 n/a 3139 n/a n/a n/a BindingDB BindingDB
159 AKT2 CHEMBL1096636 BD50316196 n/a 316 n/a n/a n/a BindingDB BindingDB
160 AKT2 6-phenylpurine compound 11 BD00016227 n/a 3200 n/a n/a n/a BindingDB BindingDB
161 AKT2 pyrazinone 14f BD00015161 n/a 325 n/a n/a n/a BindingDB BindingDB
162 AKT2 CHEMBL502393 BD50243219 n/a 33 n/a n/a n/a BindingDB BindingDB
163 AKT2 quinoxaline 16f BD00015167 n/a 332 n/a n/a n/a BindingDB BindingDB
164 AKT2 pyrazole-based inhibitor 8a BD00016220 n/a 34 n/a n/a n/a BindingDB BindingDB
165 AKT2 isoquinoline-5-sulfonamide 49 BD00015217 n/a 3400 n/a n/a n/a BindingDB BindingDB
166 AKT2 Pyridopyrimidine, 14c BD00024879 n/a 35 n/a n/a n/a BindingDB BindingDB
167 AKT2 CHEMBL597817 BD50307978 n/a 35 n/a n/a n/a BindingDB BindingDB
168 AKT2 CHEMBL597212 BD50307979 n/a 35 n/a n/a n/a BindingDB BindingDB
169 AKT2 CHEMBL443633 BD50243785 n/a 3570 n/a n/a n/a BindingDB BindingDB
170 AKT2 CHEMBL600646 BD50307980 n/a 36 n/a n/a n/a BindingDB BindingDB
171 AKT2 isoquinoline-5-sulfonamide 8 BD00015196 n/a 370 n/a n/a n/a BindingDB BindingDB
172 AKT2 2,3,5-trisubstituted pyridine, 13a BD00024893 n/a 370 n/a n/a n/a BindingDB BindingDB
173 AKT2 2,3,5-trisubstituted pyridine, 10a BD00024885 n/a 38 n/a n/a n/a BindingDB BindingDB
174 AKT2 quinoxaline 16b BD00015163 n/a 388 n/a n/a n/a BindingDB BindingDB
175 AKT2 CHEMBL596290 BD50305881 n/a 39 n/a n/a n/a BindingDB BindingDB
176 AKT2 isoquinoline-5-sulfonamide 23 BD00015208 n/a 3900 n/a n/a n/a BindingDB BindingDB
177 AKT2 oxadiazole-containing compound, 2 BD00024990 n/a 3980 n/a n/a n/a BindingDB BindingDB
178 AKT2 oxadiazole-containing compound, 3d BD00025010 n/a 4 n/a n/a n/a BindingDB BindingDB
179 AKT2 CHEMBL443661 BD50243216 n/a 4 n/a n/a n/a BindingDB BindingDB
180 AKT2 CHEMBL597600 BD50307957 n/a 4 n/a n/a n/a BindingDB BindingDB
181 AKT2 CHEMBL599849 BD50307956 n/a 4.9 n/a n/a n/a BindingDB BindingDB
182 AKT2 CHEMBL1096291 BD50316189 39 40 n/a n/a n/a BindingDB BindingDB
183 AKT2 CHEMBL453288 BD50243272 n/a 40 n/a n/a n/a BindingDB BindingDB
184 AKT2 CHEMBL447348 BD50243779 n/a 40 n/a n/a n/a BindingDB BindingDB
185 AKT2 CHEMBL1097974 BD50316187 n/a 40 n/a n/a n/a BindingDB BindingDB
186 AKT2 6-phenylpurine compound 13 BD00016228 n/a 400 n/a n/a n/a BindingDB BindingDB
187 AKT2 CHEMBL590109 BD50305006 n/a 4200 n/a n/a n/a BindingDB BindingDB
188 AKT2 tetrazolylypyridine 8d BD00015182 n/a 422 n/a n/a n/a BindingDB BindingDB
189 AKT2 CHEMBL499554 BD50243286 n/a 43 n/a n/a n/a BindingDB BindingDB
190 AKT2 CHEMBL488654 BD50243764 n/a 43 n/a n/a n/a BindingDB BindingDB
191 AKT2 6-phenylpurine compound 14 BD00016229 n/a 430 n/a n/a n/a BindingDB BindingDB
192 AKT2 CHEMBL1258898 BD50327806 n/a 433 n/a n/a n/a BindingDB BindingDB
193 AKT2 CHEMBL1258441 BD50327798 n/a 4371 n/a n/a n/a BindingDB BindingDB
194 AKT2 Pyridopyrimidine, 11 BD00024883 n/a 44 n/a n/a n/a BindingDB BindingDB
195 AKT2 CHEMBL447114 BD50243217 n/a 44 n/a n/a n/a BindingDB BindingDB
196 AKT2 CHEMBL598439 BD50307981 n/a 44 n/a n/a n/a BindingDB BindingDB
197 AKT2 CHEMBL500993 BD50243765 n/a 45 n/a n/a n/a BindingDB BindingDB
198 AKT2 pyrazinone 14e BD00015159 n/a 4517 n/a n/a n/a BindingDB BindingDB
199 AKT2 CHEMBL598438 BD50307982 n/a 46 n/a n/a n/a BindingDB BindingDB
200 AKT2 CHEMBL508754 BD50243770 n/a 47 n/a n/a n/a BindingDB BindingDB
201 AKT2 CHEMBL449989 BD50243285 n/a 48 n/a n/a n/a BindingDB BindingDB
202 AKT2 isoquinoline-5-sulfonamide 50 BD00015218 n/a 480 n/a n/a n/a BindingDB BindingDB
203 AKT2 isoquinoline-5-sulfonamide 17 BD00015202 n/a 4800 n/a n/a n/a BindingDB BindingDB
204 AKT2 cyanopyridine 7b BD00015173 n/a 4811 n/a n/a n/a BindingDB BindingDB
205 AKT2 Pyridopyrimidine, 12j BD00024865 n/a 494 n/a n/a n/a BindingDB BindingDB
206 AKT2 CHEMBL1257281 BD50327760 n/a 4951 n/a n/a n/a BindingDB BindingDB
207 AKT2 Isoquinoline-pyridine, 10a BD00016954 n/a 5 n/a n/a n/a BindingDB BindingDB
208 AKT2 Isoquinoline-pyridine, 10e BD00016958 n/a 5 n/a n/a n/a BindingDB BindingDB
209 AKT2 oxadiazole-containing compound, 14b BD00025016 n/a 5 n/a n/a n/a BindingDB BindingDB
210 AKT2 CHEMBL598842 BD50307958 n/a 5 n/a n/a n/a BindingDB BindingDB
211 AKT2 CHEMBL596991 BD50307959 n/a 5.5 n/a n/a n/a BindingDB BindingDB
212 AKT2 CHEMBL598206 BD50307960 n/a 5.7 n/a n/a n/a BindingDB BindingDB
213 AKT2 CHEMBL1099298 BD50316185 105 50 n/a n/a n/a BindingDB BindingDB
214 AKT2 CHEMBL1098944 BD50316199 n/a 50 n/a n/a n/a BindingDB BindingDB
215 AKT2 CHEMBL513728 BD50278769 800 500 n/a n/a n/a BindingDB BindingDB
216 AKT2 CHEMBL1257280 BD50327759 n/a 5027 n/a n/a n/a BindingDB BindingDB
217 AKT2 2,3,5-trisubstituted pyridine, 10e BD00024889 n/a 51 n/a n/a n/a BindingDB BindingDB
218 AKT2 pyrazole-based inhibitor 6 BD00016216 n/a 510 n/a n/a n/a BindingDB BindingDB
219 AKT2 Pyridopyrimidine, 13d BD00024871 n/a 5127 n/a n/a n/a BindingDB BindingDB
220 AKT2 CHEMBL590957 BD50307944 n/a 52 n/a n/a n/a BindingDB BindingDB
221 AKT2 isoquinoline-5-sulfonamide 65 BD00015221 n/a 520 n/a n/a n/a BindingDB BindingDB
222 AKT2 isoquinoline-5-sulfonamide 40 BD00015214 n/a 5200 n/a n/a n/a BindingDB BindingDB
223 AKT2 pyrazole-based inhibitor 3 BD00016213 n/a 5200 n/a n/a n/a BindingDB BindingDB
224 AKT2 Pyridopyrimidine, 12k BD00024866 n/a 529 n/a n/a n/a BindingDB BindingDB
225 AKT2 CHEMBL506434 BD50243784 n/a 539 n/a n/a n/a BindingDB BindingDB
226 AKT2 pyrazinone 14d BD00015157 n/a 5407 n/a n/a n/a BindingDB BindingDB
227 AKT2 CHEMBL446779 BD50256721 n/a 55.1 n/a n/a n/a BindingDB BindingDB
228 AKT2 CHEMBL1258778 BD50327804 n/a 5586 n/a n/a n/a BindingDB BindingDB
229 AKT2 Pyridopyrimidine, 13h BD00024875 n/a 57 n/a n/a n/a BindingDB BindingDB
230 AKT2 isoquinoline-5-sulfonamide 4 BD00015192 n/a 570 n/a n/a n/a BindingDB BindingDB
231 AKT2 CHEMBL603675 BD50307945 n/a 58 n/a n/a n/a BindingDB BindingDB
232 AKT2 Pyridopyrimidine, 14b BD00024878 n/a 59 n/a n/a n/a BindingDB BindingDB
233 AKT2 CHEMBL448196 BD50243786 n/a 59 n/a n/a n/a BindingDB BindingDB
234 AKT2 CHEMBL496690 BD50278837 2 6 n/a n/a n/a BindingDB BindingDB
235 AKT2 oxadiazole-containing compound, 14a BD00025015 n/a 6 n/a n/a n/a BindingDB BindingDB
236 AKT2 CHEMBL263664 BD50237622 n/a 6 n/a n/a n/a BindingDB BindingDB
237 AKT2 CHEMBL447168 BD50243780 n/a 6 n/a n/a n/a BindingDB BindingDB
238 AKT2 CHEMBL594933 BD50305883 n/a 6 n/a n/a n/a BindingDB BindingDB
239 AKT2 Staurosporine BD00002579 n/a 6.5 n/a n/a n/a BindingDB BindingDB
240 AKT2 CHEMBL506077 BD50256715 n/a 6.7 n/a n/a n/a BindingDB BindingDB
241 AKT2 pyridine-base inhibitor 13a BD00015067 n/a 6.8 n/a n/a n/a BindingDB BindingDB
242 AKT2 2,3,5-trisubstituted pyridine, 13c BD00024895 n/a 62 n/a n/a n/a BindingDB BindingDB
243 AKT2 CHEMBL524998 BD50278834 40 63 n/a n/a n/a BindingDB BindingDB
244 AKT2 CHEMBL594523 BD50306160 n/a 63 n/a n/a n/a BindingDB BindingDB
245 AKT2 CHEMBL1098241 BD50316186 n/a 63 n/a n/a n/a BindingDB BindingDB
246 AKT2 CHEMBL1099281 BD50316200 n/a 63 n/a n/a n/a BindingDB BindingDB
247 AKT2 CHEMBL1258551 BD50327801 n/a 630 n/a n/a n/a BindingDB BindingDB
248 AKT2 CHEMBL593573 BD50306162 n/a 6300 n/a n/a n/a BindingDB BindingDB
249 AKT2 2,3,5-trisubstituted pyridine, 13b BD00024894 n/a 64 n/a n/a n/a BindingDB BindingDB
250 AKT2 quinoxaline 16c BD00015164 n/a 65 n/a n/a n/a BindingDB BindingDB
251 AKT2 isoquinoline-5-sulfonamide 11 BD00015199 n/a 6600 n/a n/a n/a BindingDB BindingDB
252 AKT2 isoquinoline-5-sulfonamide 25 BD00015212 n/a 6600 n/a n/a n/a BindingDB BindingDB
253 AKT2 cyanopyridine 7c BD00015174 n/a 6650 n/a n/a n/a BindingDB BindingDB
254 AKT2 CHEMBL499683 BD50243774 n/a 67 n/a n/a n/a BindingDB BindingDB
255 AKT2 CHEMBL455071 BD50243283 n/a 68 n/a n/a n/a BindingDB BindingDB
256 AKT2 CHEMBL605326 BD50307952 n/a 680 n/a n/a n/a BindingDB BindingDB
257 AKT2 CHEMBL603244 BD50307946 n/a 69 n/a n/a n/a BindingDB BindingDB
258 AKT2 6-phenylpurine compound 6 BD00016224 n/a 6900 n/a n/a n/a BindingDB BindingDB
259 AKT2 CHEMBL605410 BD50306164 n/a 7 n/a n/a n/a BindingDB BindingDB
260 AKT2 CHEMBL603882 BD50307961 n/a 7 n/a n/a n/a BindingDB BindingDB
261 AKT2 CHEMBL604910 BD50307962 n/a 7 n/a n/a n/a BindingDB BindingDB
262 AKT2 CHEMBL598841 BD50307947 n/a 70 n/a n/a n/a BindingDB BindingDB
263 AKT2 CHEMBL1257163 BD50327757 n/a 707 n/a n/a n/a BindingDB BindingDB
264 AKT2 2,3,5-trisubstituted pyridine, 10g BD00024891 n/a 73 n/a n/a n/a BindingDB BindingDB
265 AKT2 CHEMBL448926 BD50243776 n/a 73 n/a n/a n/a BindingDB BindingDB
266 AKT2 oxadiazole-containing compound, 9 BD00024996 n/a 741 n/a n/a n/a BindingDB BindingDB
267 AKT2 H-8 BD00015210 n/a 7600 n/a n/a n/a BindingDB BindingDB
268 AKT2 CHEMBL450545 BD50243768 n/a 77 n/a n/a n/a BindingDB BindingDB
269 AKT2 CHEMBL442919 BD50256722 n/a 77.9 n/a n/a n/a BindingDB BindingDB
270 AKT2 isoquinoline-5-sulfonamide 41 BD00015215 n/a 780 n/a n/a n/a BindingDB BindingDB
271 AKT2 CHEMBL482537 BD50278100 16 79 n/a n/a n/a BindingDB BindingDB
272 AKT2 CHEMBL1098943 BD50316198 n/a 79 n/a n/a n/a BindingDB BindingDB
273 AKT2 oxadiazole-containing compound, 3b BD00025008 n/a 8 n/a n/a n/a BindingDB BindingDB
274 AKT2 oxadiazole-containing compound, 3f BD00025012 n/a 8 n/a n/a n/a BindingDB BindingDB
275 AKT2 CHEMBL488428 BD50243218 n/a 8 n/a n/a n/a BindingDB BindingDB
276 AKT2 CHEMBL498052 BD50278835 n/a 8 n/a n/a n/a BindingDB BindingDB
277 AKT2 CHEMBL597793 BD50307954 n/a 8 n/a n/a n/a BindingDB BindingDB
278 AKT2 CHEMBL604507 BD50307963 n/a 8 n/a n/a n/a BindingDB BindingDB
279 AKT2 CHEMBL597414 BD50307955 n/a 8.5 n/a n/a n/a BindingDB BindingDB
280 AKT2 CHEMBL455226 BD50243273 n/a 80 n/a n/a n/a BindingDB BindingDB
281 AKT2 isoquinoline-5-sulfonamide 22 BD00015207 n/a 8100 n/a n/a n/a BindingDB BindingDB
282 AKT2 CHEMBL452823 BD50243214 n/a 827 n/a n/a n/a BindingDB BindingDB
283 AKT2 CHEMBL1258329 BD50327796 n/a 8362 n/a n/a n/a BindingDB BindingDB
284 AKT2 CHEMBL445212 BD50243275 n/a 84 n/a n/a n/a BindingDB BindingDB
285 AKT2 CHEMBL602236 BD50307948 n/a 84 n/a n/a n/a BindingDB BindingDB
286 AKT2 isoquinoline-5-sulfonamide 19 BD00015204 n/a 8700 n/a n/a n/a BindingDB BindingDB
287 AKT2 CHEMBL1258899 BD50327756 n/a 872 n/a n/a n/a BindingDB BindingDB
288 AKT2 cyanopyridine 7e BD00015176 n/a 8740 n/a n/a n/a BindingDB BindingDB
289 AKT2 Pyridopyrimidine, 12b BD00024857 n/a 8923 n/a n/a n/a BindingDB BindingDB
290 AKT2 CHEMBL162 BD50059889 n/a 9 44 n/a n/a BindingDB BindingDB
291 AKT2 CHEMBL523586 BD50278836 0.63 9 n/a n/a n/a BindingDB BindingDB
292 AKT2 6-phenylpurine compound 16 BD00016230 n/a 9 n/a n/a n/a BindingDB BindingDB
293 AKT2 oxadiazole-containing compound, 3a BD00025007 n/a 9 n/a n/a n/a BindingDB BindingDB
294 AKT2 CHEMBL448991 BD50243783 n/a 9 n/a n/a n/a BindingDB BindingDB
295 AKT2 CHEMBL1171647 BD50322393 n/a 9 n/a n/a n/a BindingDB BindingDB
296 AKT2 CHEMBL499555 BD50256714 n/a 9.4 n/a n/a n/a BindingDB BindingDB
297 AKT2 Pyridopyrimidine, 12l BD00024867 n/a 90 n/a n/a n/a BindingDB BindingDB
298 AKT2 2,3,5-trisubstituted pyridine, 10d BD00024888 n/a 90 n/a n/a n/a BindingDB BindingDB
299 AKT2 CHEMBL605212 BD50307949 n/a 90 n/a n/a n/a BindingDB BindingDB
300 AKT2 CHEMBL443620 BD50243284 n/a 92 n/a n/a n/a BindingDB BindingDB
301 AKT2 Pyridopyrimidine, 13a BD00024868 n/a 928 n/a n/a n/a BindingDB BindingDB
302 AKT2 CHEMBL442718 BD50243763 n/a 93 n/a n/a n/a BindingDB BindingDB
303 AKT2 Pyridopyrimidine, 14d BD00024880 n/a 94 n/a n/a n/a BindingDB BindingDB
304 AKT2 6-phenylpurine compound 10 BD00016226 n/a 9500 n/a n/a n/a BindingDB BindingDB
305 AKT2 isoquinoline-5-sulfonamide 7 BD00015195 n/a 960 n/a n/a n/a BindingDB BindingDB
306 AKT2 CHEMBL503652 BD50243280 n/a 98 n/a n/a n/a BindingDB BindingDB
307 AKT2 Pyridopyrimidine, 2 BD00024882 n/a 99 n/a n/a n/a BindingDB BindingDB
308 AKT2 GSK_690693 GSK_690693 n/a n/a 2.1 n/a n/a NB2011DRx NB2011DRx
309 AKT2 CHEMBL603469 BD50308060 n/a n/a 2100 n/a n/a BindingDB BindingDB
310 AKT2 CEP_701 CEP_701 n/a n/a 2100 n/a n/a NB2011DRx NB2011DRx
311 AKT2 SU11248 BD00004814 n/a n/a 2700 n/a n/a BindingDB BindingDB
312 AKT2 Sunitinib Sunitinib n/a n/a 2700 n/a n/a NB2008 NB2008
313 AKT2 Sunitinib Sunitinib n/a n/a 2700 n/a n/a NB2011DRx NB2011DRx
314 AKT2 A_674563 A_674563 n/a n/a 2900 n/a n/a NB2011DRx NB2011DRx
315 AKT2 Staurosporine Staurosporine n/a n/a 44 n/a n/a NB2008 NB2008
316 AKT2 Staurosporine Staurosporine n/a n/a 44 n/a n/a NB2011DRx NB2011DRx
317 AKT2 CHEBI:668343 BD50298227 n/a n/a 780 n/a n/a BindingDB BindingDB
318 AKT2 CHEMBL608533 BD50326053 n/a n/a 780 n/a n/a BindingDB BindingDB
319 AKT2 PKC_412 PKC_412 n/a n/a 780 n/a n/a NB2008 NB2008
320 AKT2 PKC_412 PKC_412 n/a n/a 780 n/a n/a NB2011DRx NB2011DRx
321 AKT2 LY_333531 LY_333531 n/a n/a 8700 n/a n/a NB2011DRx NB2011DRx
322 AKT2 CHEMBL362016 BD50325992 325 n/a n/a n/a n/a BindingDB BindingDB
323 AKT2 CHEMBL498051 BD50278833 40 n/a n/a n/a n/a BindingDB BindingDB
324 AKT2 CHEMBL248757 BD50224883 4800 n/a n/a n/a n/a BindingDB BindingDB
325 AKT2 ANP ANP n/a n/a n/a n/a n/a PDB PDB
326 AKT2 CAS135897_06_2 CAS135897_06_2 n/a n/a n/a n/a 48.52 NB2011RBC NB2011RBC
327 AKT2 CAS62996_74_1 CAS62996_74_1 n/a n/a n/a n/a 5.51 NB2011RBC NB2011RBC
328 AKT2 G93 G93 n/a n/a n/a n/a n/a PDB PDB
329 AKT2 G95 G95 n/a n/a n/a n/a n/a PDB PDB
330 AKT2 G96 G96 n/a n/a n/a n/a n/a PDB PDB
331 AKT2 G98 G98 n/a n/a n/a n/a n/a PDB PDB
332 AKT2 GVP GVP n/a n/a n/a n/a n/a PDB PDB
333 AKT2 I5S I5S n/a n/a n/a n/a n/a PDB PDB
334 AKT2 L20 L20 n/a n/a n/a n/a n/a PDB PDB
335 AKT2 X37 X37 n/a n/a n/a n/a n/a PDB PDB
336 AKT2 X39 X39 n/a n/a n/a n/a n/a PDB PDB