Summary of query kinase
Query kinase CDK9 (P50750)
Kinase group CMGC
Number of inhibitors 117
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 CDK9 CHEMBL489833 BD50267607 n/a 1220 n/a n/a n/a BindingDB BindingDB
1 CDK9 CHEMBL484990 BD50279338 n/a 15 n/a n/a n/a BindingDB BindingDB
2 CDK9 4-Arylazo-3,5-diamino-1H-pyrazole 30b BD00012027 n/a 1500 n/a n/a n/a BindingDB BindingDB
3 CDK9 CHEMBL455194 BD50246360 n/a 1500 n/a n/a n/a BindingDB BindingDB
4 CDK9 CHEMBL508506 BD50246414 n/a 1600 n/a n/a n/a BindingDB BindingDB
5 CDK9 CHEMBL424696 BD50186373 n/a 2.5 n/a n/a n/a BindingDB BindingDB
6 CDK9 FLAVOPIRIDOL BD50088605 n/a 20 6.4 n/a n/a BindingDB BindingDB
7 CDK9 imidazo[2,1-f]-1,2,4-triazine, 13 BD00027219 n/a 200 n/a n/a n/a BindingDB BindingDB
8 CDK9 (R)-Roscovitine BD00007533 n/a 230 >10000 n/a n/a BindingDB BindingDB
9 CDK9 CHEMBL210540 BD50186375 n/a 2500 n/a n/a n/a BindingDB BindingDB
10 CDK9 CHEMBL212049 BD50186374 n/a 26 n/a n/a n/a BindingDB BindingDB
11 CDK9 CHEMBL454646 BD50246416 n/a 270 n/a n/a n/a BindingDB BindingDB
12 CDK9 Pyrrolopyridinone, 89S BD00027380 n/a 28 n/a n/a n/a BindingDB BindingDB
13 CDK9 CHEMBL162 BD50059889 n/a 3.3 100 n/a n/a BindingDB BindingDB
14 CDK9 Staurosporine BD00002579 n/a 3.3 n/a n/a n/a BindingDB BindingDB
15 CDK9 CHEMBL455450 BD50246464 n/a 3200 n/a n/a n/a BindingDB BindingDB
16 CDK9 Pyrrolopyridinone, 1 BD00027344 n/a 34 n/a n/a n/a BindingDB BindingDB
17 CDK9 CAN508 BD00012028 n/a 350 n/a n/a n/a BindingDB BindingDB
18 CDK9 CHEMBL1823556 BD50352019 n/a 350 n/a n/a n/a BindingDB BindingDB
19 CDK9 CHEMBL495557 BD50293176 n/a 3500 n/a n/a n/a BindingDB BindingDB
20 CDK9 CHEMBL454645 BD50246415 n/a 370 n/a n/a n/a BindingDB BindingDB
21 CDK9 BMS-387072 BD00005931 n/a 4 76 n/a n/a BindingDB BindingDB
22 CDK9 CHEMBL452602 BD50246466 n/a 4 n/a n/a n/a BindingDB BindingDB
23 CDK9 CHEMBL510566 BD50246467 n/a 4100 n/a n/a n/a BindingDB BindingDB
24 CDK9 pyrazolo[1,5-a]-1,3,5-triazine, 7a BD00027217 n/a 43 n/a n/a n/a BindingDB BindingDB
25 CDK9 CHEMBL522590 BD50267523 n/a 5400 n/a n/a n/a BindingDB BindingDB
26 CDK9 BMS-387032 analog 19 BD00005929 n/a 550 n/a n/a n/a BindingDB BindingDB
27 CDK9 4-Arylazo-3,5-diamino-1H-pyrazole 26b BD00012025 n/a 5600 n/a n/a n/a BindingDB BindingDB
28 CDK9 CHEMBL498738 BD50279061 n/a 6100 n/a n/a n/a BindingDB BindingDB
29 CDK9 CHEMBL455195 BD50246361 n/a 680 n/a n/a n/a BindingDB BindingDB
30 CDK9 CHEMBL452601 BD50246465 n/a 770 n/a n/a n/a BindingDB BindingDB
31 CDK9 CHEMBL509012 BD50246413 n/a 810 n/a n/a n/a BindingDB BindingDB
32 CDK9 CHEMBL525012 BD50279099 n/a 95 n/a n/a n/a BindingDB BindingDB
33 CDK9 Pyrrolopyridinone, 89R BD00027379 n/a 96 n/a n/a n/a BindingDB BindingDB
34 CDK9 CHEMBL496567 BD50293174 n/a 97 n/a n/a n/a BindingDB BindingDB
35 CDK9 Staurosporine Staurosporine n/a n/a 100 n/a n/a NB2008 NB2008
36 CDK9 Staurosporine Staurosporine n/a n/a 100 n/a n/a NB2011DRx NB2011DRx
37 CDK9 LY_317615 LY_317615 n/a n/a 1300 n/a n/a NB2011DRx NB2011DRx
38 CDK9 R547 R547 n/a n/a 15 n/a n/a NB2011DRx NB2011DRx
39 CDK9 EXEL_2880 EXEL_2880 n/a n/a 1600 n/a n/a NB2011DRx NB2011DRx
40 CDK9 A_674563 A_674563 n/a n/a 180 n/a n/a NB2011DRx NB2011DRx
41 CDK9 PHA_665752 PHA_665752 n/a n/a 1800 n/a n/a NB2011DRx NB2011DRx
42 CDK9 cid_11409972 BD00031085 n/a n/a 190 n/a n/a BindingDB BindingDB
43 CDK9 AST_487 AST_487 n/a n/a 190 n/a n/a NB2008 NB2008
44 CDK9 AST_487 AST_487 n/a n/a 190 n/a n/a NB2011DRx NB2011DRx
45 CDK9 BMS_345541 BMS_345541 n/a n/a 1900 n/a n/a NB2011DRx NB2011DRx
46 CDK9 ABT-869 BD00021079 n/a n/a 3000 n/a n/a BindingDB BindingDB
47 CDK9 ABT_869 ABT_869 n/a n/a 3000 n/a n/a NB2008 NB2008
48 CDK9 ABT_869 ABT_869 n/a n/a 3000 n/a n/a NB2011DRx NB2011DRx
49 CDK9 CHEMBL1082152 BD50312990 n/a n/a 410 n/a n/a BindingDB BindingDB
50 CDK9 JNJ-7706621 BD00006866 n/a n/a 470 n/a n/a BindingDB BindingDB
51 CDK9 JNJ_7706621 JNJ_7706621 n/a n/a 470 n/a n/a NB2008 NB2008
52 CDK9 AT_7519 AT_7519 n/a n/a 5.8 n/a n/a NB2011DRx NB2011DRx
53 CDK9 CHEMBL603469 BD50308060 n/a n/a 530 n/a n/a BindingDB BindingDB
54 CDK9 CEP_701 CEP_701 n/a n/a 530 n/a n/a NB2011DRx NB2011DRx
55 CDK9 Flavopiridol Flavopiridol n/a n/a 6.4 n/a n/a NB2008 NB2008
56 CDK9 Flavopiridol Flavopiridol n/a n/a 6.4 n/a n/a NB2011DRx NB2011DRx
57 CDK9 cid_24867231 BD00031099 n/a n/a 6400 n/a n/a BindingDB BindingDB
58 CDK9 BMS_387032 BMS_387032 n/a n/a 76 n/a n/a NB2008 NB2008
59 CDK9 BMS_387032 BMS_387032 n/a n/a 76 n/a n/a NB2011DRx NB2011DRx
60 CDK9 TG_101348 TG_101348 n/a n/a 8800 n/a n/a NB2011DRx NB2011DRx
61 CDK9 CDK Inhibitor, 6 BD00081433 0.29 n/a n/a n/a n/a BindingDB BindingDB
62 CDK9 CDK Inhibitor, 14 BD00081441 0.38 n/a n/a n/a n/a BindingDB BindingDB
63 CDK9 CDK Inhibitor, 3 BD00081430 0.8 n/a n/a n/a n/a BindingDB BindingDB
64 CDK9 CDK Inhibitor, 7 BD00081434 0.96 n/a n/a n/a n/a BindingDB BindingDB
65 CDK9 CDK Inhibitor, 12 BD00081439 1.9 n/a n/a n/a n/a BindingDB BindingDB
66 CDK9 CHEMBL1083151 BD50319623 11 n/a n/a n/a n/a BindingDB BindingDB
67 CDK9 CHEMBL1083786 BD50319627 1153 n/a n/a n/a n/a BindingDB BindingDB
68 CDK9 CDK Inhibitor, 11 BD00081438 14 n/a n/a n/a n/a BindingDB BindingDB
69 CDK9 CHEMBL1083484 BD50319626 1472 n/a n/a n/a n/a BindingDB BindingDB
70 CDK9 CHEMBL1084629 BD50319618 2605 n/a n/a n/a n/a BindingDB BindingDB
71 CDK9 CHEMBL1084969 BD50319616 264 n/a n/a n/a n/a BindingDB BindingDB
72 CDK9 CHEMBL1084454 BD50319624 337 n/a n/a n/a n/a BindingDB BindingDB
73 CDK9 CHEMBL1083150 BD50319625 348 n/a n/a n/a n/a BindingDB BindingDB
74 CDK9 CHEMBL298445 BD50229973 4 n/a n/a n/a n/a BindingDB BindingDB
75 CDK9 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 32 BD00008061 4 n/a n/a n/a n/a BindingDB BindingDB
76 CDK9 CDK Inhibitor, 4 BD00081431 4.3 n/a n/a n/a n/a BindingDB BindingDB
77 CDK9 CDK Inhibitor, 5 BD00081432 4.3 n/a n/a n/a n/a BindingDB BindingDB
78 CDK9 CDK Inhibitor, 2 BD00081429 4.5 n/a n/a n/a n/a BindingDB BindingDB
79 CDK9 CHEMBL1083785 BD50319615 448 n/a n/a n/a n/a BindingDB BindingDB
80 CDK9 CHEMBL482967 BD50277583 480 n/a n/a n/a n/a BindingDB BindingDB
81 CDK9 CDK Inhibitor, 8 BD00081435 5.9 n/a n/a n/a n/a BindingDB BindingDB
82 CDK9 CDK Inhibitor, 13 BD00081440 5.9 n/a n/a n/a n/a BindingDB BindingDB
83 CDK9 CHEMBL1084630 BD50319617 559 n/a n/a n/a n/a BindingDB BindingDB
84 CDK9 CHEMBL1086088 BD50319621 564 n/a n/a n/a n/a BindingDB BindingDB
85 CDK9 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 37 BD00008066 575 n/a n/a n/a n/a BindingDB BindingDB
86 CDK9 CHEMBL1083152 BD50319622 6 n/a n/a n/a n/a BindingDB BindingDB
87 CDK9 CDK Inhibitor, 9 BD00081436 6.7 n/a n/a n/a n/a BindingDB BindingDB
88 CDK9 CDK Inhibitor, 10 BD00081437 8.5 n/a n/a n/a n/a BindingDB BindingDB
89 CDK9 CHEMBL1084715 BD50319620 9 n/a n/a n/a n/a BindingDB BindingDB
90 CDK9 ANP ANP n/a n/a n/a n/a n/a PDB PDB
91 CDK9 ATP ATP n/a n/a n/a n/a n/a PDB PDB
92 CDK9 CAS135897_06_2 CAS135897_06_2 n/a n/a n/a n/a 15.76 NB2011RBC NB2011RBC
93 CDK9 CAS136194_77_9 CAS136194_77_9 n/a n/a n/a n/a 46.76 NB2011RBC NB2011RBC
94 CDK9 CAS142273_20_9 CAS142273_20_9 n/a n/a n/a n/a 31.48 NB2011RBC NB2011RBC
95 CDK9 CAS151342_35_7 CAS151342_35_7 n/a n/a n/a n/a 43.46 NB2011RBC NB2011RBC
96 CDK9 CAS190654_01_4 CAS190654_01_4 n/a n/a n/a n/a 46.94 NB2011RBC NB2011RBC
97 CDK9 CAS237430_03_4 CAS237430_03_4 n/a n/a n/a n/a 24.19 NB2011RBC NB2011RBC
98 CDK9 CAS326914_10_7 CAS326914_10_7 n/a n/a n/a n/a 40.07 NB2011RBC NB2011RBC
99 CDK9 CAS345987_15_7 CAS345987_15_7 n/a n/a n/a n/a 26.61 NB2011RBC NB2011RBC
100 CDK9 CAS443797_96_4 CAS443797_96_4 n/a n/a n/a n/a 27.41 NB2011RBC NB2011RBC
101 CDK9 CAS443798_55_8 CAS443798_55_8 n/a n/a n/a n/a 7.46 NB2011RBC NB2011RBC
102 CDK9 CAS496864_16_5 CAS496864_16_5 n/a n/a n/a n/a 42.78 NB2011RBC NB2011RBC
103 CDK9 CAS608512_97_6 CAS608512_97_6 n/a n/a n/a n/a 23.83 NB2011RBC NB2011RBC
104 CDK9 CAS62996_74_1 CAS62996_74_1 n/a n/a n/a n/a 9.24 NB2011RBC NB2011RBC
105 CDK9 CAS667463_62_9 CAS667463_62_9 n/a n/a n/a n/a 37.49 NB2011RBC NB2011RBC
106 CDK9 CAS784211_09_2 CAS784211_09_2 n/a n/a n/a n/a 21.61 NB2011RBC NB2011RBC
107 CDK9 CAS852045_46_6 CAS852045_46_6 n/a n/a n/a n/a 39.84 NB2011RBC NB2011RBC
108 CDK9 CAS852527_97_0 CAS852527_97_0 n/a n/a n/a n/a 23.72 NB2011RBC NB2011RBC
109 CDK9 CAS854171_35_0 CAS854171_35_0 n/a n/a n/a n/a 33.17 NB2011RBC NB2011RBC
110 CDK9 CAS856436_16_3 CAS856436_16_3 n/a n/a n/a n/a 45.87 NB2011RBC NB2011RBC
111 CDK9 CAS866405_64_3 CAS866405_64_3 n/a n/a n/a n/a 36.68 NB2011RBC NB2011RBC
112 CDK9 CAS896138_40_2 CAS896138_40_2 n/a n/a n/a n/a 49.53 NB2011RBC NB2011RBC
113 CDK9 CAS97161_97_2 CAS97161_97_2 n/a n/a n/a n/a 25.42 NB2011RBC NB2011RBC
114 CDK9 CPB CPB n/a n/a n/a n/a n/a PDB PDB
115 CDK9 RFZ RFZ n/a n/a n/a n/a n/a PDB PDB
116 CDK9 SLQ SLQ n/a n/a n/a n/a n/a PDB PDB