Summary of query kinase
Query kinase DYRK2 (Q92630)
Kinase group CMGC
Number of inhibitors 79
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 DYRK2 CHEMBL1803072 BD50347761 n/a 100 n/a n/a n/a BindingDB BindingDB
1 DYRK2 CHEMBL1802851 BD50347768 n/a 10000 n/a n/a n/a BindingDB BindingDB
2 DYRK2 CHEMBL1802357 BD50347749 n/a 110 n/a n/a n/a BindingDB BindingDB
3 DYRK2 CHEMBL37139 BD50087427 n/a 1100 n/a n/a n/a BindingDB BindingDB
4 DYRK2 CHEMBL1803070 BD50347759 n/a 1100 n/a n/a n/a BindingDB BindingDB
5 DYRK2 CHEMBL1803079 BD50347740 n/a 120 n/a n/a n/a BindingDB BindingDB
6 DYRK2 CHEMBL1803073 BD50347762 n/a 120 n/a n/a n/a BindingDB BindingDB
7 DYRK2 CHEMBL485053 BD50292406 n/a 1500 n/a n/a n/a BindingDB BindingDB
8 DYRK2 CHEMBL1803082 BD50347743 n/a 160 n/a n/a n/a BindingDB BindingDB
9 DYRK2 CHEMBL1802855 BD50347772 n/a 1600 n/a n/a n/a BindingDB BindingDB
10 DYRK2 CHEMBL1802854 BD50347771 n/a 2000 n/a n/a n/a BindingDB BindingDB
11 DYRK2 CHEMBL1802846 BD50347763 n/a 210 n/a n/a n/a BindingDB BindingDB
12 DYRK2 CHEMBL1803080 BD50347741 n/a 2100 n/a n/a n/a BindingDB BindingDB
13 DYRK2 CHEMBL1802841 BD50347754 n/a 2200 n/a n/a n/a BindingDB BindingDB
14 DYRK2 CHEMBL191384 BD50169959 n/a 300 n/a n/a n/a BindingDB BindingDB
15 DYRK2 CHEMBL1803068 BD50347777 n/a 3300 n/a n/a n/a BindingDB BindingDB
16 DYRK2 CHEMBL1802849 BD50347766 n/a 340 n/a n/a n/a BindingDB BindingDB
17 DYRK2 CHEMBL1802358 BD50347750 n/a 35 n/a n/a n/a BindingDB BindingDB
18 DYRK2 CHEMBL1802356 BD50347748 n/a 40 n/a n/a n/a BindingDB BindingDB
19 DYRK2 CHEMBL1803069 BD50347778 n/a 460 n/a n/a n/a BindingDB BindingDB
20 DYRK2 CHEMBL1803083 BD50347744 n/a 47 n/a n/a n/a BindingDB BindingDB
21 DYRK2 CHEMBL1802853 BD50347770 n/a 470 n/a n/a n/a BindingDB BindingDB
22 DYRK2 CHEMBL1803071 BD50347760 n/a 510 n/a n/a n/a BindingDB BindingDB
23 DYRK2 CHEMBL1802856 BD50347774 n/a 5100 n/a n/a n/a BindingDB BindingDB
24 DYRK2 CHEMBL1802844 BD50347757 n/a 530 n/a n/a n/a BindingDB BindingDB
25 DYRK2 CHEMBL1802843 BD50347756 n/a 550 n/a n/a n/a BindingDB BindingDB
26 DYRK2 CHEMBL1802847 BD50347764 n/a 560 n/a n/a n/a BindingDB BindingDB
27 DYRK2 CHEMBL1803067 BD50347776 n/a 560 n/a n/a n/a BindingDB BindingDB
28 DYRK2 CHEMBL1803085 BD50347746 n/a 60 n/a n/a n/a BindingDB BindingDB
29 DYRK2 CHEMBL1802850 BD50347767 n/a 6000 n/a n/a n/a BindingDB BindingDB
30 DYRK2 CHEMBL1803084 BD50347745 n/a 61 n/a n/a n/a BindingDB BindingDB
31 DYRK2 CHEMBL1802845 BD50347758 n/a 610 n/a n/a n/a BindingDB BindingDB
32 DYRK2 CHEMBL1802848 BD50347765 n/a 620 n/a n/a n/a BindingDB BindingDB
33 DYRK2 CHEMBL81714 BD50145371 n/a 6300 n/a n/a n/a BindingDB BindingDB
34 DYRK2 CHEMBL1802842 BD50347755 n/a 640 n/a n/a n/a BindingDB BindingDB
35 DYRK2 CHEMBL1802857 BD50347775 n/a 6500 n/a n/a n/a BindingDB BindingDB
36 DYRK2 CHEMBL1179821 BD50347773 n/a 710 n/a n/a n/a BindingDB BindingDB
37 DYRK2 CHEMBL1802852 BD50347769 n/a 770 n/a n/a n/a BindingDB BindingDB
38 DYRK2 CHEMBL1802355 BD50347747 n/a 80 n/a n/a n/a BindingDB BindingDB
39 DYRK2 HARMINE BD50047019 n/a 900 n/a n/a n/a BindingDB BindingDB
40 DYRK2 CHEMBL265470 BD50298224 n/a 950 n/a n/a n/a BindingDB BindingDB
41 DYRK2 Erlotinib Erlotinib n/a n/a 1300 n/a n/a NB2011DRx NB2011DRx
42 DYRK2 SU_14813 SU_14813 n/a n/a 1300 n/a n/a NB2011DRx NB2011DRx
43 DYRK2 BMS_387032 BMS_387032 n/a n/a 1700 n/a n/a NB2011DRx NB2011DRx
44 DYRK2 BIBW_2992 BIBW_2992 n/a n/a 1800 n/a n/a NB2011DRx NB2011DRx
45 DYRK2 EXEL_2880 EXEL_2880 n/a n/a 2000 n/a n/a NB2011DRx NB2011DRx
46 DYRK2 AST_487 AST_487 n/a n/a 210 n/a n/a NB2011DRx NB2011DRx
47 DYRK2 BMS_345541 BMS_345541 n/a n/a 2100 n/a n/a NB2011DRx NB2011DRx
48 DYRK2 CHEMBL603469 BD50308060 n/a n/a 22 n/a n/a BindingDB BindingDB
49 DYRK2 CEP_701 CEP_701 n/a n/a 22 n/a n/a NB2011DRx NB2011DRx
50 DYRK2 Staurosporine Staurosporine n/a n/a 250 n/a n/a NB2011DRx NB2011DRx
51 DYRK2 PLX_4720 PLX_4720 n/a n/a 2700 n/a n/a NB2011DRx NB2011DRx
52 DYRK2 INCB18424 INCB18424 n/a n/a 3700 n/a n/a NB2011DRx NB2011DRx
53 DYRK2 KW_2449 KW_2449 n/a n/a 390 n/a n/a NB2011DRx NB2011DRx
54 DYRK2 Crizotinib Crizotinib n/a n/a 4000 n/a n/a NB2011DRx NB2011DRx
55 DYRK2 PI_103 PI_103 n/a n/a 4100 n/a n/a NB2011DRx NB2011DRx
56 DYRK2 R406 R406 n/a n/a 470 n/a n/a NB2011DRx NB2011DRx
57 DYRK2 CHEMBL1474834 BD50342916 n/a n/a 480 n/a n/a BindingDB BindingDB
58 DYRK2 AT_7519 AT_7519 n/a n/a 5400 n/a n/a NB2011DRx NB2011DRx
59 DYRK2 TG_100_115 TG_100_115 n/a n/a 5600 n/a n/a NB2011DRx NB2011DRx
60 DYRK2 PP_242 PP_242 n/a n/a 59 n/a n/a NB2011DRx NB2011DRx
61 DYRK2 CHIR_258 CHIR_258 n/a n/a 6000 n/a n/a NB2011DRx NB2011DRx
62 DYRK2 A_674563 A_674563 n/a n/a 63 n/a n/a NB2011DRx NB2011DRx
63 DYRK2 CI_1033 CI_1033 n/a n/a 6700 n/a n/a NB2011DRx NB2011DRx
64 DYRK2 SU11248 BD00004814 n/a n/a 680 n/a n/a BindingDB BindingDB
65 DYRK2 Sunitinib Sunitinib n/a n/a 680 n/a n/a NB2011DRx NB2011DRx
66 DYRK2 GDC_0941 GDC_0941 n/a n/a 7600 n/a n/a NB2011DRx NB2011DRx
67 DYRK2 CAS129_56_6 CAS129_56_6 n/a n/a n/a n/a 14.2 NB2011RBC NB2011RBC
68 DYRK2 CAS135897_06_2 CAS135897_06_2 n/a n/a n/a n/a 5.94 NB2011RBC NB2011RBC
69 DYRK2 CAS136194_77_9 CAS136194_77_9 n/a n/a n/a n/a 48.94 NB2011RBC NB2011RBC
70 DYRK2 CAS300801_52_9 CAS300801_52_9 n/a n/a n/a n/a 19.53 NB2011RBC NB2011RBC
71 DYRK2 CAS345987_15_7 CAS345987_15_7 n/a n/a n/a n/a 22.16 NB2011RBC NB2011RBC
72 DYRK2 CAS608512_97_6 CAS608512_97_6 n/a n/a n/a n/a 12.09 NB2011RBC NB2011RBC
73 DYRK2 CAS648450_29_7 CAS648450_29_7 n/a n/a n/a n/a 39.81 NB2011RBC NB2011RBC
74 DYRK2 CAS852527_97_0 CAS852527_97_0 n/a n/a n/a n/a 46.84 NB2011RBC NB2011RBC
75 DYRK2 CAS856436_16_3 CAS856436_16_3 n/a n/a n/a n/a 3.11 NB2011RBC NB2011RBC
76 DYRK2 CAS866405_64_3 CAS866405_64_3 n/a n/a n/a n/a 47.05 NB2011RBC NB2011RBC
77 DYRK2 CAS97161_97_2 CAS97161_97_2 n/a n/a n/a n/a 9.9 NB2011RBC NB2011RBC
78 DYRK2 IRB IRB n/a n/a n/a n/a n/a PDB PDB