Summary of query kinase
Query kinase MAP3K9 (P80192)
Kinase group TKL
Number of inhibitors 119
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 MAP3K9 5-oxo dihydronaphthylcarbazole analogue, 15 BD00024948 n/a 101 n/a n/a n/a BindingDB BindingDB
1 MAP3K9 5-oxo dihydronaphthylcarbazole analogue, 14 BD00024947 n/a 103 n/a n/a n/a BindingDB BindingDB
2 MAP3K9 Pyrrolocarbazole Analog 9 BD00014178 n/a 1106 n/a n/a n/a BindingDB BindingDB
3 MAP3K9 Pyrrolocarbazole Analog 20 BD00014179 n/a 111 n/a n/a n/a BindingDB BindingDB
4 MAP3K9 K-252c BD00002581 n/a 138 n/a n/a n/a BindingDB BindingDB
5 MAP3K9 Lactam Analog 26 BD00014181 n/a 1415 n/a n/a n/a BindingDB BindingDB
6 MAP3K9 CHEMBL289772 BD50108296 n/a 15 n/a n/a n/a BindingDB BindingDB
7 MAP3K9 CHEMBL288817 BD50108295 n/a 16 n/a n/a n/a BindingDB BindingDB
8 MAP3K9 CHEMBL288818 BD50108294 n/a 162 n/a n/a n/a BindingDB BindingDB
9 MAP3K9 Pyrrolocarbazole Analog 5 BD00014173 n/a 167 n/a n/a n/a BindingDB BindingDB
10 MAP3K9 Pyrrolocarbazole Analog 19 BD00014175 n/a 1795 n/a n/a n/a BindingDB BindingDB
11 MAP3K9 5-oxo dihydronaphthylcarbazole analogue, 8 BD00024943 n/a 188 n/a n/a n/a BindingDB BindingDB
12 MAP3K9 CHEMBL277817 BD50108293 n/a 19 n/a n/a n/a BindingDB BindingDB
13 MAP3K9 Imide Analog 7 BD00014186 n/a 22 n/a n/a n/a BindingDB BindingDB
14 MAP3K9 K-252a BD00006760 n/a 22 n/a n/a n/a BindingDB BindingDB
15 MAP3K9 5-oxo dihydronaphthylcarbazole analogue, 16 BD00024949 n/a 26 n/a n/a n/a BindingDB BindingDB
16 MAP3K9 CHEMBL288229 BD50108299 n/a 28 n/a n/a n/a BindingDB BindingDB
17 MAP3K9 Imide Analog 12 BD00014187 n/a 300 n/a n/a n/a BindingDB BindingDB
18 MAP3K9 CHEMBL29709 BD50108298 n/a 303 n/a n/a n/a BindingDB BindingDB
19 MAP3K9 Pyrrolocarbazole Analog 21 BD00014176 n/a 308 n/a n/a n/a BindingDB BindingDB
20 MAP3K9 CHEMBL38338 BD50108300 n/a 360 n/a n/a n/a BindingDB BindingDB
21 MAP3K9 CEP-1347 BD00024942 n/a 38 n/a n/a n/a BindingDB BindingDB
22 MAP3K9 CHEMBL481968 BD50255048 n/a 4000 n/a n/a n/a BindingDB BindingDB
23 MAP3K9 CHEMBL36891 BD50108291 n/a 43 n/a n/a n/a BindingDB BindingDB
24 MAP3K9 CHEMBL288816 BD50108297 n/a 45 n/a n/a n/a BindingDB BindingDB
25 MAP3K9 Pyrrolocarbazole Analog 8 BD00014174 n/a 46 n/a n/a n/a BindingDB BindingDB
26 MAP3K9 Lactam Analog 37 BD00014183 n/a 482 n/a n/a n/a BindingDB BindingDB
27 MAP3K9 5-oxo dihydronaphthylcarbazole analogue, 19 BD00024952 n/a 49 n/a n/a n/a BindingDB BindingDB
28 MAP3K9 CHEMBL465465 BD50255012 n/a 5000 n/a n/a n/a BindingDB BindingDB
29 MAP3K9 CHEMBL1084926 BD50312613 n/a 591 n/a n/a n/a BindingDB BindingDB
30 MAP3K9 Lactam Analog 38 BD00014184 n/a 615 n/a n/a n/a BindingDB BindingDB
31 MAP3K9 5-oxo dihydronaphthylcarbazole analogue, 9 BD00024944 n/a 66 n/a n/a n/a BindingDB BindingDB
32 MAP3K9 Imide Analog 15 BD00014188 n/a 68 n/a n/a n/a BindingDB BindingDB
33 MAP3K9 Pyrrolocarbazole Analog 6 BD00014177 n/a 69 n/a n/a n/a BindingDB BindingDB
34 MAP3K9 CHEMBL481969 BD50255049 n/a 7000 n/a n/a n/a BindingDB BindingDB
35 MAP3K9 CHEMBL37529 BD50108292 n/a 90 n/a n/a n/a BindingDB BindingDB
36 MAP3K9 CHEMBL162 BD50059889 n/a n/a 10 n/a n/a BindingDB BindingDB
37 MAP3K9 Staurosporine Staurosporine n/a n/a 10 n/a n/a NB2008 NB2008
38 MAP3K9 Staurosporine Staurosporine n/a n/a 10 n/a n/a NB2011DRx NB2011DRx
39 MAP3K9 EXEL_2880 EXEL_2880 n/a n/a 1000 n/a n/a NB2011DRx NB2011DRx
40 MAP3K9 cid_451705 BD00031096 n/a n/a 10000 n/a n/a BindingDB BindingDB
41 MAP3K9 LY333531 BD00017055 n/a n/a 1400 n/a n/a BindingDB BindingDB
42 MAP3K9 LY_333531 LY_333531 n/a n/a 1400 n/a n/a NB2008 NB2008
43 MAP3K9 LY_333531 LY_333531 n/a n/a 1400 n/a n/a NB2011DRx NB2011DRx
44 MAP3K9 CHEBI:668343 BD50298227 n/a n/a 15 n/a n/a BindingDB BindingDB
45 MAP3K9 CHEMBL608533 BD50326053 n/a n/a 15 n/a n/a BindingDB BindingDB
46 MAP3K9 CHEMBL1240703 BD50326054 n/a n/a 15 n/a n/a BindingDB BindingDB
47 MAP3K9 PKC_412 PKC_412 n/a n/a 15 n/a n/a NB2008 NB2008
48 MAP3K9 PKC_412 PKC_412 n/a n/a 15 n/a n/a NB2011DRx NB2011DRx
49 MAP3K9 BIBF_1120der BIBF_1120der n/a n/a 220 n/a n/a NB2011DRx NB2011DRx
50 MAP3K9 cid_10138259 BD00031095 n/a n/a 2600 n/a n/a BindingDB BindingDB
51 MAP3K9 SU_14813 SU_14813 n/a n/a 2600 n/a n/a NB2008 NB2008
52 MAP3K9 SU_14813 SU_14813 n/a n/a 2600 n/a n/a NB2011DRx NB2011DRx
53 MAP3K9 SKI_606 SKI_606 n/a n/a 2700 n/a n/a NB2011DRx NB2011DRx
54 MAP3K9 Pazopanib BD00026474 n/a n/a 290 n/a n/a BindingDB BindingDB
55 MAP3K9 GW_786034 GW_786034 n/a n/a 290 n/a n/a NB2008 NB2008
56 MAP3K9 Pazopanib Pazopanib n/a n/a 290 n/a n/a NB2011DRx NB2011DRx
57 MAP3K9 PP_242 PP_242 n/a n/a 2900 n/a n/a NB2011DRx NB2011DRx
58 MAP3K9 CHEMBL603469 BD50308060 n/a n/a 3.5 n/a n/a BindingDB BindingDB
59 MAP3K9 CEP_701 CEP_701 n/a n/a 3.5 n/a n/a NB2011DRx NB2011DRx
60 MAP3K9 AG_013736 AG_013736 n/a n/a 3000 n/a n/a NB2011DRx NB2011DRx
61 MAP3K9 GSK_461364A GSK_461364A n/a n/a 3000 n/a n/a NB2011DRx NB2011DRx
62 MAP3K9 TG_101348 TG_101348 n/a n/a 3200 n/a n/a NB2011DRx NB2011DRx
63 MAP3K9 SU11248 BD00004814 n/a n/a 3400 n/a n/a BindingDB BindingDB
64 MAP3K9 Sunitinib Sunitinib n/a n/a 3400 n/a n/a NB2008 NB2008
65 MAP3K9 Sunitinib Sunitinib n/a n/a 3400 n/a n/a NB2011DRx NB2011DRx
66 MAP3K9 JNJ-7706621 BD00006866 n/a n/a 3600 n/a n/a BindingDB BindingDB
67 MAP3K9 JNJ_7706621 JNJ_7706621 n/a n/a 3600 n/a n/a NB2008 NB2008
68 MAP3K9 VX-680 BD00013534 n/a n/a 390 n/a n/a BindingDB BindingDB
69 MAP3K9 VX_680 VX_680 n/a n/a 390 n/a n/a NB2008 NB2008
70 MAP3K9 VX_680 VX_680 n/a n/a 390 n/a n/a NB2011DRx NB2011DRx
71 MAP3K9 R406 R406 n/a n/a 4.3 n/a n/a NB2011DRx NB2011DRx
72 MAP3K9 PD_173955 PD_173955 n/a n/a 410 n/a n/a NB2011DRx NB2011DRx
73 MAP3K9 TAE_684 TAE_684 n/a n/a 410 n/a n/a NB2011DRx NB2011DRx
74 MAP3K9 HKI_272 HKI_272 n/a n/a 5400 n/a n/a NB2011DRx NB2011DRx
75 MAP3K9 FLAVOPIRIDOL BD50088605 n/a n/a 5700 n/a n/a BindingDB BindingDB
76 MAP3K9 Flavopiridol Flavopiridol n/a n/a 5700 n/a n/a NB2008 NB2008
77 MAP3K9 Flavopiridol Flavopiridol n/a n/a 5700 n/a n/a NB2011DRx NB2011DRx
78 MAP3K9 KW_2449 KW_2449 n/a n/a 650 n/a n/a NB2011DRx NB2011DRx
79 MAP3K9 CHEMBL522892 BD50265677 n/a n/a 9900 n/a n/a BindingDB BindingDB
80 MAP3K9 CHIR_258 CHIR_258 n/a n/a 9900 n/a n/a NB2008 NB2008
81 MAP3K9 CHIR_258 CHIR_258 n/a n/a 9900 n/a n/a NB2011DRx NB2011DRx
82 MAP3K9 CAS120685_11_2 CAS120685_11_2 n/a n/a n/a n/a 0.45 NB2011RBC NB2011RBC
83 MAP3K9 CAS129_56_6 CAS129_56_6 n/a n/a n/a n/a 33.55 NB2011RBC NB2011RBC
84 MAP3K9 CAS133052_90_1 CAS133052_90_1 n/a n/a n/a n/a 45.99 NB2011RBC NB2011RBC
85 MAP3K9 CAS135897_06_2 CAS135897_06_2 n/a n/a n/a n/a 8.72 NB2011RBC NB2011RBC
86 MAP3K9 CAS136194_77_9 CAS136194_77_9 n/a n/a n/a n/a 1.49 NB2011RBC NB2011RBC
87 MAP3K9 CAS160807_49_8 CAS160807_49_8 n/a n/a n/a n/a 19.14 NB2011RBC NB2011RBC
88 MAP3K9 CAS204005_46_9 CAS204005_46_9 n/a n/a n/a n/a 39.5 NB2011RBC NB2011RBC
89 MAP3K9 CAS212779_48_1 CAS212779_48_1 n/a n/a n/a n/a 27.24 NB2011RBC NB2011RBC
90 MAP3K9 CAS212844_53_6 CAS212844_53_6 n/a n/a n/a n/a 37.76 NB2011RBC NB2011RBC
91 MAP3K9 CAS220792_57_4 CAS220792_57_4 n/a n/a n/a n/a 7.81 NB2011RBC NB2011RBC
92 MAP3K9 CAS227449_73_2 CAS227449_73_2 n/a n/a n/a n/a 44.68 NB2011RBC NB2011RBC
93 MAP3K9 CAS237430_03_4 CAS237430_03_4 n/a n/a n/a n/a 10.49 NB2011RBC NB2011RBC
94 MAP3K9 CAS257879_35_9 CAS257879_35_9 n/a n/a n/a n/a 30.59 NB2011RBC NB2011RBC
95 MAP3K9 CAS326914_10_7 CAS326914_10_7 n/a n/a n/a n/a 49.57 NB2011RBC NB2011RBC
96 MAP3K9 CAS380843_75_4 CAS380843_75_4 n/a n/a n/a n/a 16.48 NB2011RBC NB2011RBC
97 MAP3K9 CAS404828_08_6 CAS404828_08_6 n/a n/a n/a n/a 14.78 NB2011RBC NB2011RBC
98 MAP3K9 CAS443797_96_4 CAS443797_96_4 n/a n/a n/a n/a 25.56 NB2011RBC NB2011RBC
99 MAP3K9 CAS443798_55_8 CAS443798_55_8 n/a n/a n/a n/a -0.37 NB2011RBC NB2011RBC
100 MAP3K9 CAS444723_13_1 CAS444723_13_1 n/a n/a n/a n/a 3.8 NB2011RBC NB2011RBC
101 MAP3K9 CAS444731_52_6 CAS444731_52_6 n/a n/a n/a n/a 10.56 NB2011RBC NB2011RBC
102 MAP3K9 CAS457081_03_7 CAS457081_03_7 n/a n/a n/a n/a 20.38 NB2011RBC NB2011RBC
103 MAP3K9 CAS496864_15_4 CAS496864_15_4 n/a n/a n/a n/a 39.78 NB2011RBC NB2011RBC
104 MAP3K9 CAS496864_16_5 CAS496864_16_5 n/a n/a n/a n/a 37.3 NB2011RBC NB2011RBC
105 MAP3K9 CAS507475_17_4 CAS507475_17_4 n/a n/a n/a n/a 22.61 NB2011RBC NB2011RBC
106 MAP3K9 CAS546102_60_7 CAS546102_60_7 n/a n/a n/a n/a 7.57 NB2011RBC NB2011RBC
107 MAP3K9 CAS601514_19_6 CAS601514_19_6 n/a n/a n/a n/a 16.23 NB2011RBC NB2011RBC
108 MAP3K9 CAS608512_97_6 CAS608512_97_6 n/a n/a n/a n/a 46.08 NB2011RBC NB2011RBC
109 MAP3K9 CAS622387_85_3 CAS622387_85_3 n/a n/a n/a n/a 28.12 NB2011RBC NB2011RBC
110 MAP3K9 CAS62996_74_1 CAS62996_74_1 n/a n/a n/a n/a 7.1 NB2011RBC NB2011RBC
111 MAP3K9 CAS639089_54_6 CAS639089_54_6 n/a n/a n/a n/a 38.71 NB2011RBC NB2011RBC
112 MAP3K9 CAS667463_62_9 CAS667463_62_9 n/a n/a n/a n/a 9.21 NB2011RBC NB2011RBC
113 MAP3K9 CAS852527_97_0 CAS852527_97_0 n/a n/a n/a n/a 18.22 NB2011RBC NB2011RBC
114 MAP3K9 CAS854171_35_0 CAS854171_35_0 n/a n/a n/a n/a 7.06 NB2011RBC NB2011RBC
115 MAP3K9 CAS856436_16_3 CAS856436_16_3 n/a n/a n/a n/a 18.59 NB2011RBC NB2011RBC
116 MAP3K9 CAS896138_40_2 CAS896138_40_2 n/a n/a n/a n/a 42.58 NB2011RBC NB2011RBC
117 MAP3K9 CAS97161_97_2 CAS97161_97_2 n/a n/a n/a n/a 0.36 NB2011RBC NB2011RBC
118 MAP3K9 VIN VIN n/a n/a n/a n/a n/a PDB PDB