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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK CHEK2 203
CAMK CHEK1 9
CAMK MAPKAPK2 64
TK SYK 371
-YI-MSKTLGSGACGEVKLAFER--KTCKKVAIKIISKRKFAIGS---AREADPALNVETEIEILKKL-NHPCIIKIKNFF-D----AEDYYIVLELMEGGELFDKVV--GNK-RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKI----LGETSLM-RT---LCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLS-GYPPFSEH---RTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL--
--WDLVQTLGEGAYGEVQLAVNR--VTEEAVAVKIVDMKRAVDCP---ENI-KK------EICINKML-NHENVVKFYGHRRE----GNIQYLFLEYCSGGELFDRIE--PDI-GMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNL---KISDFGLATVFR-YNNRERLL-NK---MCGTLPYVAPELLK--RREFHAEPVDVWSCGIVLTAMLA-GELPWDQP---SDSCQEYSDWKEKKTYLNPWKKI--DSAPLALLHKILVENPSARITIPDIKKDRW-Y-
KVT--SQVLGLGINGKVLQIFNK--RTQEKFALKMLQDCPKAR----------R------EVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQ-AFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKE----TTSHNSL-TT---PCYTPYYVAPEVLG---PEKYDKSCDMWSLGVIMYILLC-GYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWI--
TLE--DKELGSGNFGTVKKGYYQMKKVVKTVAVKILK-NEAN-DPALKDELL-A------EANVMQQL-DNPYIVRMIGICE-----AESWMLVMEMAELGPLNKYLQ---QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYA---KISDFGLSKAL-R-A--DENYYKAQTHGKWPVKWYAPECIN---YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGM-KGSEVTAMLEKGERMGCPAGCP------REMYDLMNLCWTYDVENRPGFAAVE----LRL
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