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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK MAPKAPK2 203
CMGC GSK3B 56
CMGC MAPK8 26
AGC PRKCA 339
KVT---SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKAR-------R-EVELHWRASQCPHIVRIVDVYENLY--AGRKCLL--IVMECLDGG--ELFSRIQD--RGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYT-SKRPNAILKLTDFGFAKE-TTSHNSLTTPCYTPYYVAPEVLG-PEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVS-----------------------------------EEVKMLIRNLLKTEPTQRMTITEFMNHPWI--------------
---YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR-------ELQIMRKL-DHCNIVRLRYFFYSSG--EKKDEVYLNLVLDYVPETVYRVA---RHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVL---KLCDFGSAKQ-LVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAH-------------PWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF--------------
---YQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYR-ELVLMKCV-NHKNIIGLLNVFTPQKSLEEFQDVY--IVMELMDA---NLCQVIQ------MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK-SDCTL---KILDFGLART-AGTSFMMTPYVVTRYYRAPEVIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGR-DYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYI--------------
--F-NFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQT------VDRLY--FVMEYVNGG--DLMYHIQ----QVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLD-SEGHI---KIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIA-YQPYGKSVDWWAYGVLLYEMLAGQPPFDGE----DEDELFQSIMEHNVSYPKSLS---------------------------------------KEAVSVCKGLMTKHPAKRLGC---------GPEGERDVREHAFF
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