Kinase profiling results of kinases in KIF 2HYYA_STI (ABL1, PDB code: 2HYY, chain A)
Template Kinase: ABL1
Template inhibitor: Imatinib

16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C C
MAPK14CMGC       
ABL1TK       
ABL2TK       
DDR1TK       
EPHA3TK       
FGFR1TK       
INSRTK       
CSF1RTK       
KITTK       
PDGFRATK       
PDGFRBTK       
LCKTK       
TEKTK       
KDRTK       
LIMK2TKL       
BRAFTKL       

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
MAPK14CMGC      
ABL1TK      
ABL2TK      
CSF1RTK      
EPHA3TK      
FGFR1TK      
INSRTK      
KDRTK      
KITTK      
LCKTK      
PDGFRATK      
PDGFRBTK      
TEKTK      
BRAFTKL