Kinase profiling results of kinases in KIF 2V7AA_627 (ABL1, PDB code: 2V7A, chain A)
Template Kinase: ABL1
Template inhibitor: 5-Amido-pyrrolopyrazole 9f

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
MAPK14CMGC  
AURKAOther  
AURKBOther  
MAP2K1STE  
ABL1TK  
TNK1TK  
TNK2TK  
EGFRTK  
JAK2TK  
JAK3TK  
LCKTK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
MAPK14CMGC  
AURKAOther  
AURKBOther  
MAP2K1STE  
ABL1TK  
EGFRTK  
JAK2TK  
JAK3TK  
LCKTK  
TNK2TK