Kinase profiling results of kinases in KIF 3H9RA_TAK (ACVR1, PDB code: 3H9R, chain A)
Template Kinase: ACVR1
Template inhibitor: dorsomorphin

15 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
ABL1TK   
ABL2TK   
CSKTK   
EPHB4TK   
FYNTK   
SRCTK   
LCKTK   
MAP3K7TKL   
BRAFTKL   
RAF1TKL   
ACVR1TKL   
ACVRL1TKL   
TGFBR1TKL   
ACVR2ATKL   
TGFBR2TKL   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
ABL1TK    
ABL2TK    
CSKTK    
EPHB4TK    
FYNTK    
LCKTK    
SRCTK    
ACVR1TKL    
ACVRL1TKL    
BRAFTKL    
MAP3K7TKL    
RAF1TKL    
TGFBR1TKL    
TGFBR2TKL