Kinase profiling results of kinases in KIF 3MTFA_A3F (ACVR1, PDB code: 3MTF, chain A)
Template Kinase: ACVR1
Template inhibitor: Erlotinib

7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ABL1TK 
EPHB4TK 
JAK2TK 
SRCTK 
LCKTK 
BRAFTKL 
ACVR1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
ABL1TK  
EPHB4TK  
JAK2TK  
LCKTK  
SRCTK  
ACVR1TKL  
BRAFTKL