Kinase profiling results of kinases in KIF 3KRWA_BA1 (ADRBK1, PDB code: 3KRW, chain A)
Template Kinase: ADRBK1
Template inhibitor: balanol

 16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT1AGC
ROCK2AGC
GRK1AGC
GRK4AGC
GRK7AGC
PRKCDAGC
PRKCEAGC
PRKCHAGC
PKN2AGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
ADRBK1AGC
ADRBK2AGC
AKT1AGC
GRK4AGC
GRK5AGC
GRK6AGC
GRK7AGC
PKN2AGC
PRKCAAGC
PRKCBAGC
PRKCBAGC
PRKCDAGC
PRKCEAGC
PRKCHAGC
PRKCZAGC
ROCK2AGC