Kinase profiling results of kinases in KIF 3E8DA_G98 (AKT2, PDB code: 3E8D, chain A)
Template Kinase: AKT2
Template inhibitor: Roscovitine

 5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
AKT2AGC 
AKT3AGC 
CDK2CMGC 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT1AGC
AKT2AGC
AKT3AGC
CDC2CMGC
CDC2CMGC
CDK2CMGC