Kinase profiling results of kinases in KIF 2I0EA_PDS (PRKCB, PDB code: 2I0E, chain A)
Template Kinase: PRKCB
Template inhibitor: bisindolylmaleimide i

40 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C
AKT2AGC    
AKT3AGC    
GRK1AGC    
GRK4AGC    
GRK7AGC    
PDPK1AGC    
PRKCDAGC    
PRKCQAGC    
PRKCEAGC    
PRKCHAGC    
PRKCIAGC    
PKN1AGC    
PKN2AGC    
CAMK2DCAMK    
CHEK1CAMK    
DAPK1CAMK    
DAPK2CAMK    
DAPK3CAMK    
STK17ACAMK    
MAPKAPK23    
PHKG1CAMK    
PIM1CAMK    
PIM2CAMK    
PIM3CAMK    
CDK2CMGC    
CDK3CMGC    
CDKL2CMGC    
CDKL5CMGC    
HIPK2CMGC    
HIPK3CMGC    
AURKCOther    
PAK3STE    
FGFR1TK    
JAK3TK    
SRCTK    
LCKTK    

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
AKT2AGC      
AKT3AGC      
GRK4AGC      
GRK7AGC      
PDPK1AGC      
PKN1AGC      
PKN2AGC      
PRKCAAGC      
PRKCBAGC      
PRKCBAGC      
PRKCDAGC      
PRKCEAGC      
PRKCHAGC      
PRKCIAGC      
PRKCQAGC      
PRKCZAGC      
CAMK2DCAMK      
CHEK1CAMK      
DAPK1CAMK      
DAPK2CAMK      
DAPK3CAMK      
MAPKAPK2CAMK      
PHKG1CAMK      
PIM1CAMK      
PIM2CAMK      
PIM3CAMK      
STK17ACAMK      
CDC2CMGC      
CDC2CMGC      
CDK2CMGC      
CDK3CMGC      
HIPK2CMGC      
HIPK3CMGC      
AURKCOther      
PAK3STE      
FGFR1TK      
JAK3TK      
LCKTK      
SRCTK