Kinase profiling results of kinases in KIF 3IOPA_8I1 (PDPK1, PDB code: 3IOP, chain A)
Template Kinase: PDPK1
Template inhibitor: 8H1

16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
AKT1AGC  
AKT2AGC  
AKT3AGC  
PDPK1AGC  
RPS6KB1AGC  
CHEK2CAMK  
CDK2CMGC  
AURKAOther  
ABL1TK  
EGFRTK  
ERBB4TK  
JAK2TK  
JAK3TK  
IRAK4TKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
AKT1AGC     
AKT2AGC     
AKT3AGC     
PDPK1AGC     
PRKCBAGC     
PRKCBAGC     
PRKCZAGC     
RPS6KB1AGC     
CHEK2CAMK     
CDK2CMGC     
AURKAOther     
ABL1TK     
EGFRTK     
ERBB4TK     
JAK2TK     
JAK3TK     
IRAK4TKL