Kinase profiling results of kinases in KIF 3NLBA_5BE (CHEK1, PDB code: 3NLB, chain A)
Template Kinase: CHEK1
Template inhibitor: 38P

44 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C C
AKT1AGC       
AKT2AGC       
AKT3AGC       
ROCK1AGC       
GRK7AGC       
PDPK1AGC       
PRKCDAGC       
PRKCQAGC       
PRKCEAGC       
PRKCHAGC       
PRKCIAGC       
PKN1AGC       
RPS6KA4AGC       
RPS6KA4CAMK       
RPS6KA5AGC       
RPS6KA5CAMK       
RPS6KB1AGC       
RPS6KA1AGC       
RPS6KA1CAMK       
RPS6KA2AGC       
RPS6KA2CAMK       
RPS6KA3AGC       
RPS6KA6AGC       
RPS6KA6CAMK       
CAMK2ACAMK       
CHEK1CAMK       
STK33CAMK       
MAPKAPK23       
PIM1CAMK       
CDK2CMGC       
CDK4CMGC       
CDK5CMGC       
CDK9CMGC       
GSK3ACMGC       
GSK3BCMGC       
MAPK10CMGC       
MAPK11CMGC       
MAPK14CMGC       
AURKAOther       
AURKBOther       
NEK2Other       
PLK1Other       
STK10STE       
SRCTK       
NTRK1TK       

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
AKT1AGC      
AKT2AGC      
AKT3AGC      
GRK7AGC      
PDPK1AGC      
PKN1AGC      
PRKCAAGC      
PRKCBAGC      
PRKCBAGC      
PRKCDAGC      
PRKCEAGC      
PRKCHAGC      
PRKCIAGC      
PRKCQAGC      
PRKCZAGC      
ROCK1AGC      
RPS6KA1AGC      
RPS6KA2AGC      
RPS6KA3AGC      
RPS6KA4AGC      
RPS6KA5AGC      
RPS6KA6AGC      
RPS6KB1AGC      
CAMK2ACAMK      
CHEK1CAMK      
MAPKAPK2CAMK      
PIM1CAMK      
STK33CAMK      
CDC2CMGC      
CDC2CMGC      
CDK2CMGC      
CDK4CMGC      
CDK5CMGC      
CDK9CMGC      
GSK3ACMGC      
GSK3BCMGC      
MAPK10CMGC      
MAPK11CMGC      
MAPK14CMGC      
AURKAOther      
AURKBOther      
NEK2Other      
PLK1Other      
STK10STE      
NTRK1TK      
SRCTK