Kinase profiling results of kinases in KIF 3QD0A_3Q4 (PDPK1, PDB code: 3QD0, chain A)
Template Kinase: PDPK1
Template inhibitor: (3s,6r)-1-[2-Amino-6-(3-Amino-2h-Indazol-6-Yl)pyrimidin-4-Yl]-6-Methyl-N-Phenylpiperidine-3-Carboxamide

 28 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C
AKT1AGC    
AKT2AGC    
AKT3AGC    
PDPK1AGC    
MAPKAPK23    
CDK2CMGC    
CDK4CMGC    
CDK5CMGC    
GSK3ACMGC    
GSK3BCMGC    
MAPK9CMGC    
MAPK14CMGC    
AURKAOther    
AURKBOther    
PLK1Other    
PLK2Other    
PLK3Other    
TTKOther    
ABL1TK    
EGFRTK    
JAK2TK    
JAK3TK    
RETTK    
LYNTK    
BRAFTKL    

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
ADRBK1AGC   
AKT1AGC   
AKT2AGC   
AKT3AGC   
PDPK1AGC   
PRKCZAGC   
MAPKAPK2CAMK   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
CDK4CMGC   
CDK5CMGC   
GSK3ACMGC   
GSK3BCMGC   
MAPK14CMGC   
MAPK9CMGC   
AURKAOther   
AURKBOther   
PLK1Other   
PLK2Other   
PLK3Other   
TTKOther   
ABL1TK   
EGFRTK   
JAK2TK   
JAK3TK   
LYNTK   
RETTK   
BRAFTKL