Kinase profiling results of kinases in KIF 3LCTA_ADP (ALK, PDB code: 3LCT, chain A)
Template Kinase: ALK
Template inhibitor: Adenosine-5'-diphosphate

19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AURKAOther
STK24STE
ABL1TK
TNK2TK
ALKTK
MERTKTK
EGFRTK
EPHA2TK
PTK2TK
FGFR1TK
FGFR2TK
IGF1RTK
INSRTK
METTK
MST1RTK
RETTK
SRCTK
HCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AURKAOther
STK24STE
ABL1TK
ALKTK
EGFRTK
EPHA2TK
FGFR1TK
FGFR2TK
HCKTK
IGF1RTK
INSRTK
MERTKTK
METTK
MST1RTK
PTK2TK
RETTK
SRCTK
TNK2TK
ZAP70TK