Kinase profiling results of kinases in KIF 2W1GA_L0G (AURKA, PDB code: 2W1G, chain A)
Template Kinase: AURKA
Template inhibitor: AT9283

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
CDK2CMGC
AURKAOther
AURKBOther
ABL1TK
JAK2TK
JAK3TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CHEK1CAMK
CDC2CMGC
CDC2CMGC
CDK2CMGC
AURKAOther
AURKBOther
ABL1TK
JAK2TK
JAK3TK