Kinase profiling results of kinases in KIF 3HA6A_2JZ (AURKA, PDB code: 3HA6, chain A)
Template Kinase: AURKA
Template inhibitor: DEL-A, 10

10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
PDPK1AGC  
CSNK2A1CMGC  
GSK3BCMGC  
MAPK10CMGC  
MAPK8CMGC  
AURKAOther  
PLK1Other  
PLK3Other  
EGFRTK  
PTK2TK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
PDPK1AGC  
CSNK2A1CMGC  
GSK3BCMGC  
MAPK10CMGC  
MAPK8CMGC  
AURKAOther  
PLK1Other  
PLK3Other  
EGFRTK  
PTK2TK