Kinase profiling results of kinases in KIF 3M11A_AKI (AURKA, PDB code: 3M11, chain A)
Template Kinase: AURKA
Template inhibitor: 1-(4-{2-[(5,6-Diphenylfuro[2,3-D]pyrimidin-4-Yl)amino]ethyl}phenyl)-3-Phenylurea

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PRKCQAGC 
MAPK9CMGC 
AURKAOther 
AURKBOther 
ABL1TK 
LCKTK 
TEKTK 
RAF1TKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PRKCQAGC
MAPK9CMGC
AURKAOther
AURKBOther
ABL1TK
LCKTK
TEKTK
RAF1TKL