Kinase profiling results of kinases in KIF 3MYGA_EML (AURKA, PDB code: 3MYG, chain A)
Template Kinase: AURKA
Template inhibitor: Roscovitine

6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
AURKAOther
AURKBOther
TNK2TK
LCKTK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CHEK1CAMK  
AURKAOther  
AURKBOther  
LCKTK  
TNK2TK  
IRAK4TKL