Kinase profiling results of kinases in KIF 3IDPA_L1E (BRAF, PDB code: 3IDP, chain A)
Template Kinase: BRAF
Template inhibitor: L1E

7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
ABL1TK   
PDGFRBTK   
LCKTK   
TEKTK   
FLT1TK   
KDRTK   
BRAFTKL   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
ABL1TK      
FLT1TK      
KDRTK      
LCKTK      
PDGFRBTK      
TEKTK      
BRAFTKL