Kinase profiling results of kinases in KIF 3II5A_831 (BRAF, PDB code: 3II5, chain A)
Template Kinase: BRAF
Template inhibitor: ABT_869

7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ABL1TK 
INSRTK 
KITTK 
LCKTK 
TEKTK 
KDRTK 
BRAFTKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
ABL1TK     
INSRTK     
KDRTK     
KITTK     
LCKTK     
TEKTK     
BRAFTKL