Kinase profiling results of kinases in KIF 3PPKA_FNI (BRAF, PDB code: 3PPK, chain A)
Template Kinase: BRAF
Template inhibitor: 3-[(5-Hydroxynaphthalen-2-Yl)amino]-N-(Pyrimidin-4-Yl)furo[2,3-C]pyridine-2-Carboxamide

 5 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK1CAMK
PLK1Other
CSF1RTK
KDRTK
BRAFTKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CHEK1CAMK
PLK1Other
CSF1RTK
KDRTK
BRAFTKL