Kinase profiling results of kinases in KIF 3PJ2A_04K (BTK, PDB code: 3PJ2, chain A)
Template Kinase: BTK
Template inhibitor: PD166285

 19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C
ABL1TK     
CSKTK     
EGFRTK     
EPHB4TK     
FGFR2TK     
FGFR3TK     
CSF1RTK     
KITTK     
PDGFRBTK     
RETTK     
FYNTK     
SRCTK     
YES1TK     
BLKTK     
HCKTK     
LCKTK     
LYNTK     
BTKTK     
KDRTK     

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
ABL1TK 
BLKTK 
BTKTK 
CSF1RTK 
CSKTK 
EGFRTK 
EPHB4TK 
FGFR2TK 
FGFR3TK 
FYNTK 
HCKTK 
KDRTK 
KITTK 
LCKTK 
LYNTK 
PDGFRBTK 
RETTK 
SRCTK 
YES1TK