Kinase profiling results of kinases in KIF 1DI8A_DTQ (CDK2, PDB code: 1DI8, chain A)
Template Kinase: CDK2
Template inhibitor: whi-p180

 26 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
PDPK1AGC  
CHEK1CAMK  
CHEK2CAMK  
CDK2CMGC  
CDK4CMGC  
MAPK14CMGC  
AURKAOther  
AURKBOther  
MAP2K1STE  
ABL1TK  
TNK2TK  
PTK2TK  
JAK2TK  
FGRTK  
FYNTK  
SRCTK  
YES1TK  
BLKTK  
HCKTK  
LCKTK  
PTK6TK  
SRMSTK  
ZAP70TK  
IRAK4TKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C C
PDPK1AGC        
PRKCAAGC        
CHEK1CAMK        
CHEK2CAMK        
CDC2CMGC        
CDC2CMGC        
CDK2CMGC        
CDK4CMGC        
MAPK14CMGC        
AURKAOther        
AURKBOther        
MAP2K1STE        
ABL1TK        
BLKTK        
FGRTK        
FYNTK        
HCKTK        
JAK2TK        
LCKTK        
PTK2TK        
PTK6TK        
SRCTK        
SRMSTK        
TNK2TK        
YES1TK        
ZAP70TK        
IRAK4TKL