Kinase profiling results of kinases in KIF 1GIJA_2PU (CDK2, PDB code: 1GIJ, chain A)
Template Kinase: CDK2
Template inhibitor: pyrazole-3-yl urea deriv. 14a

 19 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
PDPK1AGC   
CDK2CMGC   
CDK4CMGC   
CSNK2A1CMGC   
MAPK11CMGC   
MAPK14CMGC   
AURKAOther   
PLK1Other   
PLK2Other   
PLK3Other   
MAP2K1STE   
TNK2TK   
JAK2TK   
JAK3TK   
SRCTK   
LCKTK   
ITKTK   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PDPK1AGC 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK4CMGC 
CDK6CMGC 
CDK6CMGC 
CSNK2A1CMGC 
MAPK11CMGC 
MAPK14CMGC 
AURKAOther 
PLK1Other 
PLK2Other 
PLK3Other 
MAP2K1STE 
ITKTK 
JAK2TK 
JAK3TK 
LCKTK 
SRCTK 
TNK2TK