Kinase profiling results of kinases in KIF 2R3JA_SCJ (CDK2, PDB code: 2R3J, chain A)
Template Kinase: CDK2
Template inhibitor: 2r3j

 27 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
ROCK2AGC 
CDK2CMGC 
CDK4CMGC 
CDC2L6CMGC 
CDK8CMGC 
CLK4CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK14CMGC 
AURKAOther 
AURKBOther 
CHUKOther 
EIF2AK2Other 
PLK1Other 
ABL1TK 
DDR1TK 
PTK2TK 
JAK2TK 
JAK3TK 
METTK 
SRCTK 
YES1TK 
LCKTK 
PTK6TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
AKT1AGC     
ROCK2AGC     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK4CMGC     
CLK4CMGC     
GSK3ACMGC     
GSK3BCMGC     
MAPK10CMGC     
MAPK14CMGC     
AURKAOther     
AURKBOther     
CHUKOther     
PLK1Other     
ABL1TK     
JAK2TK     
JAK3TK     
LCKTK     
METTK     
PTK2TK     
PTK6TK     
SRCTK     
YES1TK