Kinase profiling results of kinases in KIF 2R3KA_SCQ (CDK2, PDB code: 2R3K, chain A)
Template Kinase: CDK2
Template inhibitor: 2r3j

28 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
AKT1AGC 
ROCK2AGC 
CHEK1CAMK 
CDK2CMGC 
CDK4CMGC 
CDC2L6CMGC 
CDK8CMGC 
CLK4CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK14CMGC 
AURKAOther 
AURKBOther 
CHUKOther 
EIF2AK2Other 
PLK1Other 
ABL1TK 
DDR1TK 
PTK2TK 
JAK2TK 
JAK3TK 
METTK 
SRCTK 
YES1TK 
LCKTK 
PTK6TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C
AKT1AGC      
ROCK2AGC      
CHEK1CAMK      
CDC2CMGC      
CDC2CMGC      
CDK2CMGC      
CDK4CMGC      
CLK4CMGC      
GSK3ACMGC      
GSK3BCMGC      
MAPK10CMGC      
MAPK14CMGC      
AURKAOther      
AURKBOther      
CHUKOther      
PLK1Other      
ABL1TK      
JAK2TK      
JAK3TK      
LCKTK      
METTK      
PTK2TK      
PTK6TK      
SRCTK      
YES1TK