Kinase profiling results of kinases in KIF 3PY0A_SU9 (CDK2, PDB code: 3PY0, chain A)
Template Kinase: CDK2
Template inhibitor: SU 9516

 25 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
STK17ACAMK
STK17BCAMK
PHKG1CAMK
PRKD1CAMK
PRKD3CAMK
CHEK2CAMK
CDK2CMGC
CDK3CMGC
CDK4CMGC
CDK5CMGC
GSK3ACMGC
GSK3BCMGC
AURKBOther
AURKCOther
EIF2AK2Other
TLK2Other
PTK2TK
JAK3TK
SRCTK
NTRK2TK
NTRK3TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PDPK1AGC    
CHEK2CAMK    
PHKG1CAMK    
PRKD1CAMK    
PRKD3CAMK    
STK17ACAMK    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
CDK3CMGC    
CDK4CMGC    
CDK5CMGC    
CDK6CMGC    
CDK6CMGC    
GSK3ACMGC    
GSK3BCMGC    
AURKBOther    
AURKCOther    
TLK2Other    
JAK3TK    
NTRK2TK    
NTRK3TK    
PTK2TK    
SRCTK    
IRAK4TKL