Kinase profiling results of kinases in KIF 1UNHA_IXM (CDK5, PDB code: 1UNH, chain A)
Template Kinase: CDK5
Template inhibitor: INDIRUBIN-3'-MONOXIME

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
CDK2CMGC
CDK5CMGC
GSK3BCMGC
AURKAOther
AURKBOther
AURKCOther

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PDPK1AGC
CDC2CMGC
CDC2CMGC
CDK2CMGC
CDK5CMGC
GSK3BCMGC
AURKAOther
AURKBOther
AURKCOther