Kinase profiling results of kinases in KIF 1XO2B_FSE (CDK6, PDB code: 1XO2, chain B)
Template Kinase: CDK6
Template inhibitor: Fisetin

 11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
STK17BCAMK
CDK2CMGC
CDK5CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK14CMGC
ABL1TK
INSRTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CDC2CMGC
CDC2CMGC
CDK2CMGC
CDK5CMGC
CDK6CMGC
CDK6CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK14CMGC
ABL1TK
INSRTK