Kinase profiling results of kinases in KIF 3BLRA_CPB (CDK9, PDB code: 3BLR, chain A)
Template Kinase: CDK9
Template inhibitor: BIIVYFLTOXDAOV-TYJDENFWSA-N

 48 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
PRKCQAGC 
RPS6KA1AGC 
RPS6KA1CAMK 
RPS6KA2AGC 
RPS6KA2CAMK 
RPS6KA6AGC 
RPS6KA6CAMK 
CAMK2BCAMK 
CAMK2DCAMK 
CAMK2GCAMK 
NUAK2CAMK 
STK17ACAMK 
STK17BCAMK 
PHKG1CAMK 
PHKG2CAMK 
PRKD2CAMK 
CDK2CMGC 
CDK3CMGC 
CDK5CMGC 
CDC2L6CMGC 
CDK8CMGC 
CDK9CMGC 
CDC2L5CMGC 
PCTK1CMGC 
PCTK2CMGC 
PCTK3CMGC 
CDK15CMGC 
PFTK1CMGC 
CDKL5CMGC 
CLK1CMGC 
CLK2CMGC 
CLK3CMGC 
DYRK1ACMGC 
DYRK1BCMGC 
HIPK1CMGC 
HIPK2CMGC 
HIPK3CMGC 
HIPK4CMGC 
GSK3ACMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK8CMGC 
ICKCMGC 
MAKCMGC 
STK35Other 
EIF2AK2Other 
JAK2TK 
IRAK4TKL 
BMPR1BTKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PRKCQAGC
RPS6KA1AGC
RPS6KA2AGC
RPS6KA6AGC
CAMK2BCAMK
CAMK2DCAMK
CAMK2GCAMK
NUAK2CAMK
PHKG1CAMK
PHKG2CAMK
PRKD2CAMK
STK17ACAMK
CDC2CMGC
CDC2CMGC
CDK2CMGC
CDK3CMGC
CDK5CMGC
CDK6CMGC
CDK6CMGC
CDK9CMGC
CLK1CMGC
CLK2CMGC
CLK3CMGC
DYRK1ACMGC
DYRK1BCMGC
GSK3ACMGC
GSK3BCMGC
HIPK1CMGC
HIPK2CMGC
HIPK3CMGC
HIPK4CMGC
MAPK10CMGC
MAPK8CMGC
JAK2TK
IRAK4TKL