Kinase profiling results of kinases in KIF 3LQ5A_SLQ (CDK9, PDB code: 3LQ5, chain A)
Template Kinase: CDK9
Template inhibitor: Roscovitine

 25 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
PRKCQAGC
RPS6KA1AGC
RPS6KA1CAMK
RPS6KA2AGC
RPS6KA2CAMK
CHEK1CAMK
DAPK1CAMK
CDK2CMGC
CDK3CMGC
CDK5CMGC
CDK9CMGC
PCTK1CMGC
CLK1CMGC
CLK2CMGC
CLK4CMGC
DYRK1ACMGC
DYRK1BCMGC
GSK3BCMGC
MAPK1CMGC
MAPK10CMGC
MAPK8CMGC
PAK4STE
JAK2TK
SRCTK
YES1TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C
AKT2AGC     
PRKCQAGC     
RPS6KA1AGC     
RPS6KA2AGC     
CHEK1CAMK     
DAPK1CAMK     
CDC2CMGC     
CDC2CMGC     
CDK2CMGC     
CDK3CMGC     
CDK5CMGC     
CDK9CMGC     
CLK1CMGC     
CLK2CMGC     
CLK4CMGC     
DYRK1ACMGC     
DYRK1BCMGC     
GSK3BCMGC     
MAPK1CMGC     
MAPK10CMGC     
MAPK8CMGC     
PAK4STE     
JAK2TK     
SRCTK     
YES1TK