Kinase profiling results of kinases in KIF 3HMOA_STU (TTK, PDB code: 3HMO, chain A)
Template Kinase: TTK
Template inhibitor: staurosporine

 27 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
PDPK1AGC  
RPS6KA1AGC  
RPS6KA1CAMK  
RPS6KA2AGC  
RPS6KA2CAMK  
RPS6KA3AGC  
RPS6KA6AGC  
RPS6KA6CAMK  
CAMK1GCAMK  
STK33CAMK  
DAPK1CAMK  
DAPK3CAMK  
PHKG1CAMK  
PHKG2CAMK  
PIM1CAMK  
PIM3CAMK  
CDK2CMGC  
CDK3CMGC  
CDK5CMGC  
CDKL1CMGC  
CDKL5CMGC  
NEK1Other  
NEK5Other  
NEK2Other  
NEK4Other  
TTKOther  
ULK3Other  
STK24STE  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PDPK1AGC    
RPS6KA1AGC    
RPS6KA2AGC    
RPS6KA3AGC    
RPS6KA6AGC    
CAMK1GCAMK    
DAPK1CAMK    
DAPK3CAMK    
PHKG1CAMK    
PHKG2CAMK    
PIM1CAMK    
PIM3CAMK    
STK33CAMK    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
CDK3CMGC    
CDK5CMGC    
CDK6CMGC    
CDK6CMGC    
NEK1Other    
NEK2Other    
NEK4Other    
TTKOther    
ULK3Other    
STK24STE