Kinase profiling results of kinases in KIF 2BRGA_DFY (CHEK1, PDB code: 2BRG, chain A)
Template Kinase: CHEK1
Template inhibitor: DFY

18 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDC42BPA1 
CHEK1CAMK 
DAPK1CAMK 
DAPK2CAMK 
DAPK3CAMK 
CDK2CMGC 
CDK5CMGC 
CDK9CMGC 
CSNK2A1CMGC 
CSNK2A2CMGC 
MAPK1CMGC 
AURKAOther 
CHUKOther 
YSK4STE 
JAK1TK 
LIMK2TKL 
BRAFTKL 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
CDC42BPAAGC   
CHEK1CAMK   
DAPK1CAMK   
DAPK2CAMK   
DAPK3CAMK   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
CDK5CMGC   
CDK9CMGC   
CSNK2A1CMGC   
CSNK2A2CMGC   
MAPK1CMGC   
AURKAOther   
CHUKOther   
JAK1TK   
BRAFTKL