Kinase profiling results of kinases in KIF 2WMUA_ZYU (CHEK1, PDB code: 2WMU, chain A)
Template Kinase: CHEK1
Template inhibitor: 4-(9h-purin-6-yl)morpholine

 6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ROCK2AGC
PRKACAAGC
CHEK1CAMK
STK33CAMK
CDK2CMGC
JAK1TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PRKACAAGC
ROCK2AGC
CHEK1CAMK
STK33CAMK
CDK2CMGC
JAK1TK