Kinase profiling results of kinases in KIF 2CN5A_ADP (CHEK2, PDB code: 2CN5, chain A)
Template Kinase: CHEK2
Template inhibitor: Adenosine-5'-diphosphate

 16 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
PDPK1AGC
PRKCIAGC
STK11CAMK
DAPK1CAMK
MAPKAPK23
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CSNK2A1CMGC
MAPK12CMGC
AURKAOther
NEK2Other
PLK1Other
OXSR1STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT2AGC
GRK6AGC
PDPK1AGC
PRKCIAGC
CHEK2CAMK
DAPK1CAMK
MAPKAPK2CAMK
PIM1CAMK
STK11CAMK
CDK2CMGC
CSNK2A1CMGC
MAPK12CMGC
AURKAOther
NEK2Other
PLK1Other
OXSR1STE